Benzeneacetic acid, a-(benzoylamino)-

Base Information

• Chemical Name: Benzeneacetic acid, a-(benzoylamino)-
• CAS No.: 29670-63-1
• Molecular Formula: C15H13NO3
• Molecular Weight: 255.273
• Mol file: 29670-63-1.mol

Synonyms:N-benzoyl-α-phenylglycine;N-benzoyl-D,L-phenylglycine;2-benzamido-2-phenylacetic acid;DL-N-benzoylphenylglycine;N-benzoyl-DL-phenylglycine;Benzoylamino-phenyl-acetic acid;phenylglycine phenylacetamide;

Chemical Property of Benzeneacetic acid, a-(benzoylamino)-

Chemical Property:

• Melting Point: 176 - 177 °C (H2O)
• PSA: 66.40000
• LogP: 2.63320

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneacetic acid, a-(benzoylamino)-

There total 17 articles about Benzeneacetic acid, a-(benzoylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzoyl chloride (98-88-4) + phenylglycin (2835-06-5) → N-benzoyl-2-phenylglycine (29670-63-1)

Guidance literature:

With sodium hydroxide; 1.) 0 deg C, 2.) 10 min, 25 deg C;

DOI:10.1021/jo00167a032

Reference yield: 48.0%

2,4-diphenyl-4H-oxazol-5-one (28687-81-2,719263-73-7) → N-benzoylbenzamide (614-28-8) + N-benzoyl-2-phenylglycine (29670-63-1)

Guidance literature:

With 18-crown-6 ether; In benzene; for 24h;

Reference yield: 27.0%

2,4-diphenyl-4H-oxazol-5-one (28687-81-2,719263-73-7) → N-benzoylbenzamide (614-28-8) + phenylglycin (2835-06-5) + N-benzoyl-2-phenylglycine (29670-63-1)

Guidance literature:

With potassium; In tetrahydrofuran; for 4h;

upstream raw materials:

ethyl 2-(benzamido)-2-phenylacetate

benzoyl chloride

phenylglycin

α-hydroxyhippuric acid

Downstream raw materials:

ethyl 2-(benzamido)-2-phenylacetate

4,4'-bis-(2,4-diphenyl-Δ²-oxazolin-5-one)

2,4,2',4'-tetraphenyl-2H,4'H-[2,4']bioxazolyl-5,5'-dione

2,4-diphenyl-4H-oxazol-5-one