(E)-phenyl(p-tolyl)methanone oxime

Base Information

• Chemical Name: (E)-phenyl(p-tolyl)methanone oxime
• CAS No.: 2998-91-6
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• DSSTox Substance ID: DTXSID601266419
• Mol file: 2998-91-6.mol

Synonyms:DTXSID601266419;(E)-phenyl(p-tolyl)methanone oxime;AKOS024355663;(1E)-(4-Methylphenyl)phenylmethanone oxime;2998-91-6

Chemical Property of (E)-phenyl(p-tolyl)methanone oxime

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 211.099714038
• Heavy Atom Count: 16
• Complexity: 235

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(=NO)C2=CC=CC=C2
• Isomeric SMILES: CC1=CC=C(C=C1)/C(=N/O)/C2=CC=CC=C2

Technology Process of (E)-phenyl(p-tolyl)methanone oxime

There total 7 articles about (E)-phenyl(p-tolyl)methanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methylbenzophenone (134-84-9) → (Z)-phenyl(p-tolyl)methanone oxime (2998-92-7) + p-tolyl phenyl ketoxime (2998-91-6)

Guidance literature:

With sodium hydroxide; ethanol; hydroxylamine hydrochloride; water;

Reference yield:

4-methylphenylboronic acid (5720-05-8) + benzohydroximoyl chloride (698-16-8) → (Z)-phenyl(p-tolyl)methanone oxime (2998-92-7) + p-tolyl phenyl ketoxime (2998-91-6)

Guidance literature:

With N,N-dimethyl-aniline; In chloroform; at 60 ℃; for 3h; Overall yield = 38 percent; Overall yield = 20.1 mg; Inert atmosphere;

DOI:10.1002/chem.202001590

Reference yield:

4-Methylbenzophenone (134-84-9) → p-tolyl phenyl ketoxime (2998-91-6)

Guidance literature:

With hydroxylamine hydrochloride; In pyridine; ethanol; for 4h; Heating;

upstream raw materials:

4-Methylbenzophenone

(E)-cyclohexyl(phenyl)methanone oxime

pyridine

ethanol

Downstream raw materials:

(Z)-phenyl(p-tolyl)methanone oxime

4-methyl-N-phenylbenzamide

4-methyl-benzophenon-(O-acetyl oxime ); acetate from anti-p-tolyl-phenyl ketoxime

(E)-α-(4-Methylphenyl)-α-phenyl-N-methylnitrone