Zinc, iodo(3-methoxyphenyl)-

Base Information

• Chemical Name: Zinc, iodo(3-methoxyphenyl)-
• CAS No.: 300825-30-3
• Molecular Formula: C7H7IOZn
• Molecular Weight: 299.426
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID50400591
• Mol file: 300825-30-3.mol

Synonyms:Zinc, iodo(3-methoxyphenyl)-;iodozinc(1+);methoxybenzene;DTXSID50400591

Chemical Property of Zinc, iodo(3-methoxyphenyl)-

Chemical Property:

• Flash Point: 1 °F
• PSA: 9.23000
• Density: 0.999 g/mL at 25oC
• LogP: 2.37860
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 297.88330
• Heavy Atom Count: 10
• Complexity: 154

Purity/Quality:

99% ^*data from raw suppliers

3-Methoxyphenylzinc iodide solution 0.5M in THF ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-14-19-36/37-40
• Safety Statements: 16-26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC=C[C-]=C1.[Zn+]I

Technology Process of Zinc, iodo(3-methoxyphenyl)-

There total 1 articles about Zinc, iodo(3-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-1-iodobenzene (766-85-8) + zinc (7440-66-6) → (3-methoxyphenyl)zinc(II) iodide (300825-30-3)

Guidance literature:

In tetrahydrofuran; other Radiation; microwave-accelerated preparation of arylzinc iodide by Rieke zinc insertion into aryl iodide under sealed vessel conditions for 10 min; THF 180°C; HPLC or MS;

DOI:10.1039/b313887a

Reference yield: 93.0%

cyclohexenone (930-68-7) + (3-methoxyphenyl)zinc(II) iodide (300825-30-3) → (R)-3-(3-methoxyphenyl)cyclohexanone

Guidance literature:

With chlorobis(ethylene)rhodium(I) dimer; N,N,N,N,-tetramethylethylenediamine; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In 1,2-dimethoxyethane; at 20 ℃; for 40h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/adsc.202001141

Reference yield: 92.0%

iodobenzene (591-50-4) + (3-methoxyphenyl)zinc(II) iodide (300825-30-3) → 3-methoxybiphenyl (2113-56-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 60 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.201801543

upstream raw materials:

3-methoxy-1-iodobenzene

zinc

Downstream raw materials:

3'-methoxy-[1,1'-biphenyl]-2-carbonitrile

3'‐methoxy‐(1,1'‐biphenyl)‐4‐carboxylic acid

(+)-(R)-[3-(3-methoxyphenyl)hept-1-yn-1-yl]trimethylsilane

tert-butyl 2-((3-methoxyphenyl)sulfonyl)acetate

Refernces

• 1、 Dhungana, Roshan K.,Giri, Ramesh,Khanal, Namrata,Shekhar, K. C.. "Nickel-Catalyzed α-Carbonylalkylarylation of Vinylarenes: Expedient Access to γ,γ-Diarylcarbonyl and Aryltetralone Derivatives". supporting information. p. 8047 - 8051. Retrieved 2020/04/30.
• 2、 Basnet, Prakash,Kc, Shekhar,Dhungana, Roshan K.,Shrestha, Bijay,Boyle, Timothy J.,Giri, Ramesh. "Synergistic Bimetallic Ni/Ag and Ni/Cu Catalysis for Regioselective γ,δ-Diarylation of Alkenyl Ketimines: Addressing β-H Elimination by in Situ Generation of Cationic Ni(II) Catalysts". supporting information. p. 15586 - 15590. Retrieved 2018/11/23.