1,2-Cyclohexanediol,1,2-diacetate

Base Information

• Chemical Name: 1,2-Cyclohexanediol,1,2-diacetate
• CAS No.: 2276-46-2
• Molecular Formula: C10H16 O4
• Molecular Weight: 200.235
• Mol file: 2276-46-2.mol

Synonyms:1,2-Cyclohexanediol,diacetate (6CI,7CI,8CI,9CI); NSC 563

Chemical Property of 1,2-Cyclohexanediol,1,2-diacetate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Cyclohexanediol,1,2-diacetate

There total 13 articles about 1,2-Cyclohexanediol,1,2-diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cyclohexane-1,2-epoxide (286-20-4) + acetic anhydride (108-24-7) → 1,2-diacetoxy-cyclohexane (2276-46-2)

Guidance literature:

With N-methylpyrrolidine-2-one hydrotribromide; at 20 ℃; for 1.5h; regioselective reaction; Neat (no solvent);

DOI:10.1080/00397911.2010.493259

Reference yield: 81.0%

cyclohexane-1,2-epoxide (286-20-4) → 1,2-diacetoxy-cyclohexane (2276-46-2)

Guidance literature:

With acetic anhydride; acetic acid; triethylamine;

Reference yield: 50.6%

cyclohexene (110-83-8) → 1,2-Cyclohexanediol (931-17-9) + rac-3-acetoxycyclohexene (76644-52-5,76704-31-9,14447-34-8,62247-41-0) + 1,2-diacetoxy-cyclohexane (2276-46-2)

Guidance literature:

With hexaaquairon(II) perchlorate; dihydrogen peroxide; acetic anhydride; In acetonitrile; at 30 ℃; for 0.0833333h;

upstream raw materials:

cyclohexane-1,2-epoxide

acetic acid

cyclohexene

cyclohexane

Downstream raw materials:

cyclohexa-1,3-diene

Refernces

• 1、 -. "PREPARATION OF DIESTERS OF (METH)ACRYLIC ACID FROM EPOXIDES". Page/Page column 23. . Retrieved 2020/03/05.
• 2、 Cottrell, Ian F.,Cowley, Andrew R.,Croft, Laura J.,Hymns, Lauren,Moloney, Mark G.,Nettleton, Ewan J.,Kirsty Smithies,Thompson, Amber L.. "Acyloxylactonisations mediated by lead tetracarboxylates". body text. p. 2537 - 2550. Retrieved 2009/08/07.