1,1'-[Ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone

Base Information

• Chemical Name: 1,1'-[Ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone
• CAS No.: 3049-29-4
• Molecular Formula: C18H18O4
• Molecular Weight: 298.339
• DSSTox Substance ID: DTXSID301199306
• Nikkaji Number: J1.226.315E
• Mol file: 3049-29-4.mol

Synonyms:Cambridge id 5148132;CBDivE_004964;SCHEMBL834525;DTXSID301199306;AKOS016375277;4,4'-(Ethylenebisoxy)bis(acetylbenzene);SR-01000395014;SR-01000395014-1;1,1'-[1,2-Ethanediylbis(oxy-4,1-phenylene)]diethanone;1-{4-[2-(4-acetyl-phenoxy)-ethoxy]-phenyl}-ethanone;1,1'-[ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone;1,1'-[1,2-Ethanediylbis(oxy-4,1-phenylene)]bis[ethanone];Ethanone, 1,1'-[1,2-ethanediylbis(oxy-4,1-phenylene)]bis-;3049-29-4

Chemical Property of 1,1'-[Ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone

Chemical Property:

• Melting Point: 161 °C (ethanol)
• Boiling Point: 473.6±30.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.141±0.06 g/cm3(Predicted)
• LogP: 3.54960
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 298.12050905
• Heavy Atom Count: 22
• Complexity: 327

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CC=C(C=C1)OCCOC2=CC=C(C=C2)C(=O)C

Technology Process of 1,1'-[Ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone

There total 4 articles about 1,1'-[Ethane-1,2-diylbis(oxybenzene-4,1-diyl)]diethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethylene dibromide (106-93-4) + 4-Hydroxyacetophenone (99-93-4) → 1,1'-<1,2-ethanediylbis(oxy-4,1-phenylene)>bisethanone (3049-29-4)

Guidance literature:

With potassium carbonate; In acetone; for 18h; Reflux;

DOI:10.3390/molecules24010199

Reference yield: 71.0%

ethylene dibromide (106-93-4) + 4-hydroxy-benzoic acid (99-96-7) → 1,1'-<1,2-ethanediylbis(oxy-4,1-phenylene)>bisethanone (3049-29-4)

Guidance literature:

With potassium carbonate; at 115 - 130 ℃; for 2h;

DOI:10.1021/jm801006v

Reference yield:

ethylene dibromide (106-93-4) + 4-Hydroxyacetophenone (99-93-4) → 1,1'-<1,2-ethanediylbis(oxy-4,1-phenylene)>bisethanone (3049-29-4)

Guidance literature:

With potassium hydroxide;

upstream raw materials:

ethylene dibromide

4-Hydroxyacetophenone

4-hydroxy-benzoic acid

Downstream raw materials:

1,2-Bis-(4-ethinyl-phenoxy)-ethan

1,2-bis(4-cinnamoylphenoxy)ethane

3-(4-{2-[4-(2-ethoxycarbonyl-1-methylvinyl)phenoxy]ethoxy}phenyl)but-2-enoic acid ethyl ester

C₃₂H₃₀N₄O₂