ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE

Base Information

• Chemical Name: ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE
• CAS No.: 30519-00-7
• Molecular Formula: C10H12O3S
• Molecular Weight: 212.269
• Mol file: 30519-00-7.mol

Synonyms:(4-hydroxyphenylsulfanyl)acetic acid ethyl ester;ethyl [(4-hydroxyphenyl)thio]acetate;4-Hydroxyphenylthioessigsaeureethylester;(4-hydroxy-phenylsulfanyl)-acetic acid ethyl ester;ethyl 2-(4-hydroxyphenylthio)acetate;Ethyl (4-Hydroxyphenylsulfanyl)acetate;

Chemical Property of ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE

Chemical Property:

• PSA: 71.83000
• LogP: 2.04740

Purity/Quality:

Ethyl 2-[(4-hydroxyphenyl)sulfanyl]acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE

There total 2 articles about ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-sulfanylphenol (637-89-8) + ethyl bromoacetate (105-36-2) → (4-Hydroxy-phenylsulfanyl)-acetic acid ethyl ester (30519-00-7)

Guidance literature:

With triethylamine; In chloroform; for 2h;

DOI:10.1021/jm0205550

Reference yield: 91.0%

→ (4-Hydroxy-phenylsulfanyl)-acetic acid ethyl ester (30519-00-7)

Guidance literature:

Reference yield: 96.0%

(4-Hydroxy-phenylsulfanyl)-acetic acid ethyl ester (30519-00-7) + 1-Bromo-2-butyne (3355-28-0) → (4-but-2-ynyloxyphenylsulfanyl)acetic acid ethyl ester (287201-52-9)

Guidance literature:

With potassium carbonate; for 8h; Heating / reflux;

upstream raw materials:

4-sulfanylphenol

ethyl bromoacetate

Downstream raw materials:

[4-(4-chlorophenoxy)phenylsulfanyl]acetic acid ethyl ester

ethyl {[4-(benzyloxy)phenyl]thio}acetate

[4-(2-ethylbutoxy)phenylsulfanyl]acetic acid ethyl ester

[4-(3-methylbutoxy)phenylsulfanyl]acetic acid ethyl ester