4-Methoxy-2-vinylpyridine

Base Information

• Chemical Name: 4-Methoxy-2-vinylpyridine
• CAS No.: 30566-80-4
• Molecular Formula: C8H9NO
• Molecular Weight: 135.166
• European Community (EC) Number: 968-335-3
• DSSTox Substance ID: DTXSID20595605
• Wikidata: Q82490662
• Mol file: 30566-80-4.mol

Synonyms:4-Methoxy-2-vinylpyridine;30566-80-4;2-ethenyl-4-methoxypyridine;2-Ethenyl-4-methoxy-pyridine;Pyridine, 2-ethenyl-4-methoxy-;SCHEMBL931557;DTXSID20595605;MFCD18384441;AKOS016002316;SB54193;AS-36185;DB-295438;CS-0267187;EN300-1831956

Chemical Property of 4-Methoxy-2-vinylpyridine

Chemical Property:

• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 135.068413911
• Heavy Atom Count: 10
• Complexity: 114

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=NC=C1)C=C

Technology Process of 4-Methoxy-2-vinylpyridine

There total 1 articles about 4-Methoxy-2-vinylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-4-nitropyridine N-oxide (5470-66-6) → 4-methoxy-2-vinylpyridine (30566-80-4)

Guidance literature:

Multi-step reaction with 4 steps

1: NaOH-solution

2: zinc; sulfuric acid; water

3: water; acetic acid / 200 °C

4: potassium hydroxide

With potassium hydroxide; sodium hydroxide; sulfuric acid; water; acetic acid; zinc;

DOI:10.1002/ardp.19582910902

Reference yield: 64.0%

4-methoxy-2-vinylpyridine (30566-80-4) + 1,3-di(aminomethyl)benzene (1477-55-0) → C40H48N6O4 (1383443-62-6)

Guidance literature:

With acetic acid; In methanol; at 60 ℃; for 120h;

DOI:10.1016/j.ica.2012.01.042

Reference yield: 32.0%

4-methoxy-2-vinylpyridine (30566-80-4) + benzylamine (100-46-9) → N-benzyl-2-(4-methoxypyridin-2-yl)ethan-1-amine

Guidance literature:

With acetic acid; In ethanol; for 16h; Reflux;

upstream raw materials:

2-methyl-4-nitropyridine N-oxide

Downstream raw materials:

C₄₀H₄₈N₆O₄