2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane

Base Information

Chemical Name:2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane
CAS No.:82117-19-9
Molecular Formula:C12H14BrClO2
Molecular Weight:305.599
Hs Code.:
NSC Number:130047
DSSTox Substance ID:DTXSID80299399
Wikidata:Q82041788

Synonyms:82117-19-9;2-(4-bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane;NSC130047;SCHEMBL1594054;DTXSID80299399;NSC-130047

Suppliers and Price of 2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane

Chemical Property:

Vapor Pressure:3.43E-05mmHg at 25°C
Boiling Point:364.9°C at 760 mmHg
Flash Point:174.5°C
Density:1.42g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:303.98657
Heavy Atom Count:16
Complexity:211

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(O1)(CCCCl)C2=CC=C(C=C2)Br

Technology Process of 2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane

There total 3 articles about 2-(4-Bromophenyl)-2-(3-chloropropyl)-1,3-dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 107-21-1
ethylene glycol

: 4559-96-0
1-(4-bromophenyl)-4-chlorobutan-1-one

: 82117-19-9
2-(3-chloropropyl)-2-(4-bromophenyl)-1,3-dioxolane

Guidance literature:: With toluene-4-sulfonic acid; In benzene; Heating;
DOI:10.1007/s10593-005-0265-6

Reference yield:

: 4559-96-0
1-(4-bromophenyl)-4-chlorobutan-1-one

: 82117-19-9
2-(3-chloropropyl)-2-(4-bromophenyl)-1,3-dioxolane

Guidance literature:: With p-toluenesulfonic acid monohydrate; sodium hydrogencarbonate; In ethylene glycol; benzene;

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 82117-19-9
2-(3-chloropropyl)-2-(4-bromophenyl)-1,3-dioxolane

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / 2.08 h / 0 - 20 °C

2: toluene-4-sulfonic acid / benzene / 10 h / Reflux; Dean-Stark

With aluminum (III) chloride; toluene-4-sulfonic acid; In benzene; 1: |Friedel-Crafts Acylation;
DOI:10.1134/S1068162015010069