6-bromo-4-morpholin-4-ylquinazoline

Base Information

Chemical Name:6-bromo-4-morpholin-4-ylquinazoline
CAS No.:307538-52-9
Molecular Formula:C12H12BrN3O
Molecular Weight:294.151
Hs Code.:
Mol file:307538-52-9.mol

Synonyms:6-bromoquinolone;6-bromo-4-morpholinoquinazoline;6-bromo-4-morpholin-4-yl-quinazoline;6-bromo-4-oxo-4H-quinoline;6-bromo-1H-quinolin-4-one;

Suppliers and Price of 6-bromo-4-morpholin-4-ylquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(6-Bromoquinazolin-4-yl)morpholine 95+%
1g
$ 470.00

Chemenu
4-(6-Bromoquinazolin-4-yl)morpholine 95%
1g
$ 444.00

ChemBridge Corporation
6-bromo-4-morpholin-4-ylquinazoline 95%
250 mg
$ 84.00

Alichem
4-(6-Bromoquinazolin-4-yl)morpholine
1g
$ 400.67

Alichem
4-(6-Bromoquinazolin-4-yl)morpholine
250mg
$ 157.56

Total 2 raw suppliers

Chemical Property of 6-bromo-4-morpholin-4-ylquinazoline

Chemical Property:

Boiling Point:448.5±45.0 °C(Predicted)
PKA:9.15±0.50(Predicted)
PSA：38.25000
Density:1.552±0.06 g/cm3(Predicted)
LogP:2.29390

Purity/Quality:

99% ^*data from raw suppliers

4-(6-Bromoquinazolin-4-yl)morpholine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-bromo-4-morpholin-4-ylquinazoline

There total 5 articles about 6-bromo-4-morpholin-4-ylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 110-91-8,99108-56-2
morpholine

: 38267-96-8
6-bromo-4-chloroquinozoline

: 307538-52-9
4-(6-bromoquinazolin-4-yl)morpholine

Guidance literature:: In 1,4-dioxane; at 150 ℃; for 0.333333h; Microwave;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 307538-52-9
4-(6-bromoquinazolin-4-yl)morpholine

Guidance literature:: Multi-step reaction with 4 steps

1: bromine; acetic acid

2: acetic acid / Reflux

3: trichlorophosphate; pyridine / 2 h / Heating

4: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / Reflux

With pyridine; bromine; acetic acid; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1039/d1nj03749h

Reference yield:

: 5794-88-7
5-Bromo-2-aminobenzoic acid

: 307538-52-9
4-(6-bromoquinazolin-4-yl)morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / Reflux

2: trichlorophosphate; pyridine / 2 h / Heating

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / Reflux

With pyridine; acetic acid; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In N,N-dimethyl-formamide;
DOI:10.1039/d1nj03749h