1-Propanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[2-methyl-

Base Information

• Chemical Name: 1-Propanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[2-methyl-
• CAS No.: 3133-29-7
• Molecular Formula: C14H18O5
• Molecular Weight: 266.294
• Hs Code.: 2914400090
• Mol file: 3133-29-7.mol

Synonyms:2,4-diisobutyrylphloroglucinol;Diisobutyrylphloroglucinol;

Chemical Property of 1-Propanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[2-methyl-

Chemical Property:

• Melting Point: 133–135°C
• PSA: 94.83000
• LogP: 2.48080

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[2-methyl-

There total 5 articles about 1-Propanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis[2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,5-dihydroxyphenol (108-73-6) + isobutyryl chloride (79-30-1) → 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis(2-methylpropan-1-one) (3133-29-7)

Guidance literature:

With treated natural zeolite mordenite; In neat (no solvent); at 20 - 80 ℃; for 0.5h; Inert atmosphere; Green chemistry;

DOI:10.1080/00397911.2019.1666282

Reference yield: 58.0%

3,5-dihydroxyphenol (108-73-6) + isobutyryl chloride (79-30-1) → phlorisobutyrophenone (35458-21-0) + 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis(2-methylpropan-1-one) (3133-29-7)

Guidance literature:

With aluminum (III) chloride; In nitrobenzene; at 65 ℃; for 21h; Inert atmosphere;

DOI:10.1021/acs.jnatprod.6b00224

Reference yield: 55.0%

3,5-dihydroxyphenol (108-73-6) + isobutyric Acid (79-31-2) → 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis(2-methylpropan-1-one) (3133-29-7)

Guidance literature:

With boron trifluoride diethyl etherate; at 100 ℃; for 2h;

DOI:10.1016/j.bmcl.2008.10.085

upstream raw materials:

3,5-dihydroxyphenol

isobutyric Acid

isobutyryl chloride

Downstream raw materials:

1,1',1'',1'''-(methylenebis(2,4,6-trihydroxybenzene-5,3,1-triyl))tetrakis(2-methylpropa n-1-one)

2,6-Diisobutyryl-filicinsaeure