3-(Benzylideneamino)pyridine

Base Information

• Chemical Name: 3-(Benzylideneamino)pyridine
• CAS No.: 32258-83-6
• Molecular Formula: C12H10N2
• Molecular Weight: 182.225
• DSSTox Substance ID: DTXSID001295585
• Nikkaji Number: J951.405H
• Mol file: 32258-83-6.mol

Synonyms:Enamine_002731;3-(Benzylideneamino)pyridine;32258-83-6;DTXSID001295585;HMS1401M03;N-(Phenylmethylene)-3-pyridinamine;N-(phenylmethylidene)pyridin-3-amine;IDI1_007078

Chemical Property of 3-(Benzylideneamino)pyridine

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 182.084398327
• Heavy Atom Count: 14
• Complexity: 183

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NC2=CN=CC=C2

Technology Process of 3-(Benzylideneamino)pyridine

There total 3 articles about 3-(Benzylideneamino)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

pyridin-3-ylamine (462-08-8) + benzyl alcohol (100-51-6,185532-71-2) → 1-phenyl-N-(pyridine-3-yl)methaneimine (32258-83-6)

Guidance literature:

With C₁₉H₃₄MnN₃O₂P₂; In toluene; at 140 ℃; for 16h; Molecular sieve; Inert atmosphere;

DOI:10.1002/chem.201603148

Reference yield: 40.0%

pyridin-3-ylamine (462-08-8) + benzaldehyde (100-52-7) → 1-phenyl-N-(pyridine-3-yl)methaneimine (32258-83-6)

Guidance literature:

With piperidine; In ethanol; for 3h; Reflux;

DOI:10.1002/cjoc.201190216

Reference yield:

pyridin-3-ylamine (462-08-8) + benzyl alcohol (100-51-6,185532-71-2) → N-(3-pyridine)benzylamine (114081-08-2) + 1-phenyl-N-(pyridine-3-yl)methaneimine (32258-83-6)

Guidance literature:

With dicarbonyl-(2,4-bis(trimethylsilyl)bicyclo[3.3.0]nona-1,4-dien-3-one)[acetonitrile]iron; In para-xylene; at 140 ℃; for 55h; Molecular sieve;

DOI:10.1002/ejoc.201900209

upstream raw materials:

pyridin-3-ylamine

benzaldehyde

benzyl alcohol

Downstream raw materials:

N-(3-pyridine)benzylamine

methyl 4-(N-benzyl-N-3-pyridylaminomethyl)-2-(2-methylphenyl)benzoate

4-(N-benzyl-N-pyridin-3-ylaminomethyl)-2-(2-methylphenyl)benzoic acid

[4-(N-benzyl-N-3-pyridylaminomethyl)-2-(2-methylphenyl)benzoyl] methionine methyl ester