4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE

Base Information

• Chemical Name: 4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE
• CAS No.: 32263-14-2
• Molecular Formula: C9H10O3
• Molecular Weight: 166.177
• Mol file: 32263-14-2.mol

Synonyms:4-Hydroxy-3-methoxy-5-methyl-benzaldehyd;4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE;5-methylvanillin;4-hydroxy-5-methoxy-3-methylbenzaldehyde;3-Methyl-4-hydroxy-5-methoxybenzaldehyd;4-hydroxy-3-methoxy-5-methylbenzaldehyde;4-hydroxy-3-methyl-5-methoxybenzaldehyde;

Chemical Property of 4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE

Chemical Property:

• PSA: 46.53000
• LogP: 1.52170

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE

There total 16 articles about 4-HYDROXY-3-METHOXY-5-METHYLBENZENECARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

sodium 4-hydroxy-3-methoxy-5-methylmandelate → 4-hydroxy-3-methoxy-5-methylbenzaldehyde (32263-14-2)

Guidance literature:

With sulfuric acid; oxygen; copper(II) oxide; at 80 ℃; for 6h; under 1125.11 Torr; pH=12; Temperature; Autoclave;

Reference yield: 93.0%

4-Hydroxy-3-methoxy-5-methyl-benzylalkohol (37987-18-1) → 4-hydroxy-3-methoxy-5-methylbenzaldehyde (32263-14-2)

Guidance literature:

With copper diacetate; ethylene glycol; at 50 ℃; for 8h; regioselective reaction; Green chemistry;

DOI:10.1039/c3gc41946k

Reference yield: 88.0%

2-methoxy-4,6-dimethylphenol (2896-66-4) → 4-hydroxy-3-methoxy-5-methylbenzaldehyde (32263-14-2)

Guidance literature:

With copper diacetate; ethylene glycol; at 65 ℃; for 12h; regioselective reaction; Green chemistry;

DOI:10.1039/c3gc41946k

upstream raw materials:

chloroform

2-methyl-6-methoxyphenol

3-(chloromethyl)-4-hydroxy-5-methoxybenzaldehyde

4-Hydroxy-3-methoxy-5-methyl-benzylalkohol

Downstream raw materials:

4-hydroxy-3-methoxy-5-methylbenzoic acid

3-amino-2,6-dichloropyridine

1,2-dimethoxy-3-methyl-5-(2-nitro-vinyl)benzene

2-(3,4-dimethoxy-5-methylphenyl)ethan-1-amine