2-Methylindolizine-1-carbonitrile

Base Information

Chemical Name:2-Methylindolizine-1-carbonitrile
CAS No.:3243-04-7
Molecular Formula:C10H8N2
Molecular Weight:156.187
Hs Code.:
DSSTox Substance ID:DTXSID50491222
Wikidata:Q82335528
Mol file:3243-04-7.mol

Synonyms:2-Methylindolizine-1-carbonitrile;3243-04-7;DTXSID50491222

Suppliers and Price of 2-Methylindolizine-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-methyl-1-Indolizinecarbonitrile 97.00%
25G
$ 3120.00

AccelPharmtech
2-methyl-1-Indolizinecarbonitrile 97.00%
5G
$ 1700.00

AccelPharmtech
2-methyl-1-Indolizinecarbonitrile 97.00%
1G
$ 1530.00

Total 3 raw suppliers

Chemical Property of 2-Methylindolizine-1-carbonitrile

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:156.068748264
Heavy Atom Count:12
Complexity:215

Purity/Quality:

95% ^*data from raw suppliers

2-methyl-1-Indolizinecarbonitrile 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN2C=CC=CC2=C1C#N

Technology Process of 2-Methylindolizine-1-carbonitrile

There total 5 articles about 2-Methylindolizine-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 4786-20-3,627-26-9
crotononitrile

: 6266-23-5
1-(carboxymethyl)pyridinium chloride

: 3243-04-7
2-methyl-3-indolizinecarbonitrile

Guidance literature:: With manganese(IV) oxide; triethylamine; In toluene; at 90 ℃; for 18h;
DOI:10.1016/j.ejps.2006.09.006

Reference yield: 50.0%

: 768-18-3
2-methylindolizine

: 870-30-4
isocyanatophosphonic dichloride

: 3243-04-7
2-methyl-3-indolizinecarbonitrile

: 2-methyl-1,3-indolizinedicarbonitrile

Guidance literature:: In 1,2-dichloro-ethane; at 20 ℃; for 2h;
DOI:10.1055/s-2002-35238

Reference yield: 48.0%

: 4-bromo-2-(pyridin-2-yl)pent-4-enenitrile

: 3243-04-7
2-methyl-3-indolizinecarbonitrile

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 10h; regioselective reaction; Sealed tube; Inert atmosphere; Green chemistry;
DOI:10.1021/acs.joc.7b01073