768-18-3

Basic information

• Product Name: 2-Methylindolizine
• Synonyms: 2-Methylindolizine;2-Methylpyrrocoline
• CAS NO: 768-18-3
• Molecular Formula: C₉H₉N
• Molecular Weight: 131.17
• Mol File: 768-18-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 59.5 °C
• Boiling Point: 75-78 °C
• Appearance: /
• Density: 1.00±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-Methylindolizine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylindolizine(768-18-3)
• EPA Substance Registry System: 2-Methylindolizine(768-18-3)

Safety Data

• Hazardous Substances Data: 768-18-3(Hazardous Substances Data)

Upstream product

• 75487-74-0 2-methyl-1-(2-oxo-propyl)-pyridinium; bromide 
• 127532-47-2 2-methyl-3-trifluoroacetylindolizine 
• 123369-00-6 2-Methyl-3-trichloroacetylindolizine 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 109-06-8 α-picoline 
• 78-95-5 chloroacetone 
• 6302-02-9 2-acetonylpyridine 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 7553-56-2 iodine 
• 67-64-1 acetone 
• 7647-01-0 hydrogenchloride 
• 25365-67-7 2-methyl-indolizine-3-carbaldehyde 
• 7732-18-5 water 

Downstream Products

• 116915-68-5 (1S,2S,2aR,7bR)-6-Methyl-1,2-diphenyl-1,2,2a,7b-tetrahydro-7a-aza-cyclobuta[e]indene 
• 108235-26-3 3-(2'-Methyl-3'-indolizinyl)-2,5-hexandion 
• 2217-55-2 bis(2,4-dinitrophenyl) disulphide 
• 76919-79-4 2-Methyl-3-pentylsulfanyl-indolizine 
• 76919-76-1 3-Ethylsulfanyl-2-methyl-indolizine 
• 76919-78-3 3-Butylsulfanyl-2-methyl-indolizine 
• 77823-57-5 (3,5-Dibromo-4-hydroxy-phenyl)-(2-methyl-indolizin-3-yl)-methanone 
• 76919-77-2 2-Methyl-3-propylsulfanyl-indolizine 
• 36944-82-8 (2-methylindolizin-3-yl)(phenyl)methanone 
• 96206-94-9 (2-methylindolizin-1-yl)(phenyl)methanone 
• 105944-62-5 2-methyl-3-(2-methylbenzoyl)indolizine 
• 88273-90-9 Toluene-4-sulfonic acid 2-chloro-4-(2-methyl-indolizine-3-carbonyl)-phenyl ester 
• 88265-21-8 Toluene-4-sulfonic acid 2-bromo-4-(2-methyl-indolizine-3-carbonyl)-phenyl ester 
• 88273-95-4 Toluene-4-sulfonic acid 2-methoxy-4-(2-methyl-indolizine-3-carbonyl)-phenyl ester 

Relevant articles and documents

NEW AMINOINDOLIZINES, DYEING COMPOSITION COMPRISING AT LEAST ONE AMINOINDOLIZINE, METHODS AND USES THEREOF

A new class of chemical entities chosen from aminoindolizines of formula (I), acid addition salts thereof, and solvates thereof: their use for dyeing keratin fibers, including human keratin fibers such as the hair; dyeing compositions comprising such chemical entities; and to kits containing compositions comprising those chemical entities.

IMDOLIZINE DERIVATIVES AS LIGANDS OF THE CRTH2 RECEPTOR

Compounds of formula (I) are CRTH2 antagonists, useful in the treatment of, for example, asthma, chronic obstructive pulmonary disease, rhinitis, allergic airway syndrome, and allergic rhinobronchitis. Formula (I) wherein R1, R2. R3 and R4 each independently are hydrogen, C1-C6alkyl, fully or partially fluorinated C1-C6alkyl, halo, -S(O)nR10, -SO2N(R10)2, -N(R10)2, -C(O)N(R10)2, -NR10C(O)R9, -CO2R10, -C(O)R9, -NO2, -CN or -OR11; wherein each R9 is independently C1-C6alkyl, aryl, heteroaryl; R10 is independently hydrogen, C1-C6alkyl, aryl, or heteroaryl; R11 is hydrogen, C1-C6alkyl, fully or partially fluorinated C1-C6alkyl or a group -SO2R10 ; n is 0, 1 or 2; R5 is C1-C6alkyl, fully or partially fluorinated C1-C6alkyl, C1-C6alkenyl, C1-C6alkynyl, optionally substituted aryl, or optionally substituted heteroaryl; R6 is hydrogen, C1-C6alkyl or fully or partially fluorinated C1-C6alkyl ; R7 and R8 are independently hydrogen or C1-C6alkyl, or R7 and R8 together with the atom to which they are attached form a cycloalkyl group; and X is -CHR6-, -S(O)n-, -C(O)-, -NR6SO2- or -SO2NR6- wherein n is 0, 1 or 2.

Compositions for dyeing keratin fibers, containing cationic indolizine derivatives, and dyeing process

Compositions for the oxidation dyeing of keratin fibres, containing at least one oxidation base and at least one coupler chosen from indolizine derivative comprising at least one cationic group Z, Z being chosen from quaternized aliphatic chains, aliphati