4-chloro-N-(2-methoxyphenyl)butanamide

Base Information

Chemical Name:4-chloro-N-(2-methoxyphenyl)butanamide
CAS No.:3245-90-7
Molecular Formula:C11H14ClNO2
Molecular Weight:227.691
Hs Code.:
DSSTox Substance ID:DTXSID801281829
Nikkaji Number:J1.220.548A
Mol file:3245-90-7.mol

Synonyms:4-chloro-N-(2-methoxyphenyl)butanamide;3245-90-7;DTXSID801281829;AKOS000151498;N-(2-Methoxyphenyl)-4-chlorobutanamide

Suppliers and Price of 4-chloro-N-(2-methoxyphenyl)butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-chloro-N-(2-methoxyphenyl)butanamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:227.0713064
Heavy Atom Count:15
Complexity:199

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1NC(=O)CCCCl

Technology Process of 4-chloro-N-(2-methoxyphenyl)butanamide

There total 4 articles about 4-chloro-N-(2-methoxyphenyl)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 90-04-0
2-methoxy-phenylamine

: 4635-59-0
4-Chlorobutanoyl chloride

: 3245-90-7
N-<4-Chlor-butyryl>-2-methoxy-anilin

Guidance literature:: With acetic acid; at 0 - 20 ℃; for 1.5h;
DOI:10.1016/S0014-827X(01)01197-1

Reference yield: 67.0%

: 4635-59-0
4-Chlorobutanoyl chloride

: 255873-36-0
tert-butyl-N-{4-[allyl(dimethyl)silyl]-2-methoxyphenyl}carbamate

: 3245-90-7
N-<4-Chlor-butyryl>-2-methoxy-anilin

Guidance literature:: Multistep reaction;
DOI:10.1016/S0040-4039(99)01817-1

Reference yield:

: 59557-91-4
4-bromo-2-methoxyaniline

: 3245-90-7
N-<4-Chlor-butyryl>-2-methoxy-anilin

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran

2: KH; t-BuLi / tetrahydrofuran / -78 °C

3: 67 percent

With tert.-butyl lithium; potassium hydride; In tetrahydrofuran; 1: Acylation / 2: silylation;
DOI:10.1016/S0040-4039(99)01817-1