5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid

Base Information

Chemical Name:5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid
CAS No.:327064-07-3
Molecular Formula:C₉H₁₀ClN₃O₃
Molecular Weight:243.65
Hs Code.:
DSSTox Substance ID:DTXSID901211051
Nikkaji Number:J2.511.758A

Synonyms:327064-07-3;5-chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid;5-chloro-2-(morpholin-4-yl)pyrimidine-4-carboxylic acid;Oprea1_771241;DTXSID901211051;HMS1784I12;MFCD02709682;STK976785;AKOS008965769;WAY-603358;CS-0244028;EN300-27106;5-Chloro-2-morpholinopyrimidine-4-carboxylicacid;5-Chloro-2-morpholinopyrimidine-4-carboxylic acid;2-(Morpholino)-5-chloropyrimidine-4-carboxylic acid;Z56794922;5-Chloro-2-(4-morpholinyl)-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylic acid, 5-chloro-2-(4-morpholinyl)-

Suppliers and Price of 5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylicacid
100mg
$ 240.00

Total 2 raw suppliers

Chemical Property of 5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid

Chemical Property:

Melting Point:119.5-120.5 °C (decomp)
Boiling Point:486.5±55.0 °C(Predicted)
PSA：75.55000
Density:1.488±0.06 g/cm3(Predicted)
LogP:0.72980
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:243.0410689
Heavy Atom Count:16
Complexity:260

Purity/Quality:

97% ^*data from raw suppliers

5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NC=C(C(=N2)C(=O)O)Cl

Technology Process of 5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid

There total 3 articles about 5-Chloro-2-morpholin-4-ylpyrimidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 110-91-8,99108-56-2
morpholine

: 38275-34-2
5-chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylic acid

: 327064-07-3
5-chloro-2-(morpholin-4-yl)-pyrimidine-4-carboxylic acid

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1080/00397910701396930

Reference yield:

: 61727-33-1
5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid

: 327064-07-3
5-chloro-2-(morpholin-4-yl)-pyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O₂; HOAc

2: 80 percent / dimethylformamide / 12 h / 20 °C

With dihydrogen peroxide; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1080/00397910701396930