4-amino-N-(2-methoxyethyl)benzenesulfonamide

Base Information

• Chemical Name: 4-amino-N-(2-methoxyethyl)benzenesulfonamide
• CAS No.: 328062-38-0
• Molecular Formula: C9H14N2O3S
• Molecular Weight: 230.288
• Mol file: 328062-38-0.mol

Synonyms:4-amino-N-(2-methoxy-ethyl)-benzenesulfonamide;4-[N-(2-Methoxyethyl)sulphamoyl]aniline;4-amino-N-(2-methoxyethyl)benzenesulfonamide;

Chemical Property of 4-amino-N-(2-methoxyethyl)benzenesulfonamide

Chemical Property:

• PSA: 89.80000
• LogP: 2.24640

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-N-(2-methoxyethyl)benzene-1-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-amino-N-(2-methoxyethyl)benzenesulfonamide

There total 3 articles about 4-amino-N-(2-methoxyethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(2-methoxy-ethyl)-4-nitro-benzenesulfonamide (321705-93-5) → 4-[N-(2-methoxyethyl)sulphamoyl]aniline (328062-38-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; at 25 ℃;

Reference yield: 65.0%

4-aminobenzenesulfonyl fluoride (98-62-4) + 2-methoxyethylamine (109-85-3) → 4-[N-(2-methoxyethyl)sulphamoyl]aniline (328062-38-0)

Guidance literature:

With triethylamine; In butan-1-ol; for 18h; Heating / reflux;

Reference yield:

4-Nitrobenzenesulfonyl chloride (98-74-8) → 4-[N-(2-methoxyethyl)sulphamoyl]aniline (328062-38-0)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 2 h

2: hydrogen / palladium 10% on activated carbon / methanol / 25 °C

With hydrogen; palladium 10% on activated carbon; In methanol; dichloromethane;

upstream raw materials:

4-aminobenzenesulfonyl fluoride

2-methoxyethylamine

N-(2-methoxy-ethyl)-4-nitro-benzenesulfonamide

4-Nitrobenzenesulfonyl chloride

Downstream raw materials:

5-Cyano-4-cyclopropylamino-2-{4-[N-(2-methoxyethyl)sulphamoyl]anilino}pyrimidine

C₁₅H₁₇N₃O₄S

5-bromo-2-{4-[N-(2-methoxy-ethyl)sulphamoyl]anilino}-4-(imidazo[1,2-a]pyrid-3-yl)pyrimidine