2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole

Base Information

Chemical Name:2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole
CAS No.:328918-81-6
Molecular Formula:C11H9BrClNO
Molecular Weight:286.556
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90449808
Nikkaji Number:J2.119.910I
Wikidata:Q82269326
Mol file:328918-81-6.mol

Synonyms:2-(4-BROMOPHENYL)-4-(CHLOROMETHYL)-5-METHYLOXAZOLE;328918-81-6;2-(4-bromophenyl)-4-(chloromethyl)-5-methyl-1,3-oxazole;SCHEMBL5023940;DTXSID90449808;WUMQZKBNFDQXFK-UHFFFAOYSA-N;4-bromophenyl-4-(chloromethyl)-5-methyloxazole

Suppliers and Price of 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole 97%
1g
$ 428.00

American Custom Chemicals Corporation
2-(4-BROMOPHENYL)-4-(CHLOROMETHYL)-5-METHYLOXAZOLE 95.00%
5MG
$ 497.26

Total 1 raw suppliers

Chemical Property of 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole

Chemical Property:

PSA：26.03000
LogP:4.15130
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:284.95560
Heavy Atom Count:15
Complexity:209

Purity/Quality:: 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC=C(C=C2)Br)CCl

Technology Process of 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole

There total 5 articles about 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 176961-51-6
2-(4-bromophenyl)-4,5-dimethyl-1,3-oxazole

: 328918-81-6
2-(4-bromophenyl)-4-(chloromethyl)-5-methyl-1,3-oxazole

: 2-(4-bromophenyl)-5-(chloromethyl)-4-methyl-1,3-oxazole

Guidance literature:: With N-chloro-succinimide; In acetonitrile; at 60 ℃;
DOI:10.1055/s-2004-834862

Reference yield: 72.0%

: 328918-80-5
4,5-dimethyl-2-(4-bromophenyl)-oxazole oxide

: 328918-81-6
2-(4-bromophenyl)-4-(chloromethyl)-5-methyl-1,3-oxazole

Guidance literature:: With trichlorophosphate; In chloroform;
DOI:10.1016/j.bmcl.2004.09.031

Reference yield:

: 1122-91-4
4-bromo-benzaldehyde

: 328918-81-6
2-(4-bromophenyl)-4-(chloromethyl)-5-methyl-1,3-oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / aq. HCl; AcOH / 0.58 h / 0 °C

2: 72 percent / POCl₃ / CHCl₃ / 0.5 h / Heating

With hydrogenchloride; acetic acid; trichlorophosphate; In chloroform;
DOI:10.1021/jm0155188