2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid

Base Information

Chemical Name:2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid
CAS No.:328918-82-7
Molecular Formula:C₁₂H₁₀BrNO₃
Molecular Weight:296.12
Hs Code.:
European Community (EC) Number:890-279-2
DSSTox Substance ID:DTXSID801243445

Synonyms:328918-82-7;2-[2-(4-bromophenyl)-5-methyl-1,3-oxazol-4-yl]acetic Acid;2-(2-(4-BROMOPHENYL)-5-METHYLOXAZOL-4-YL)ACETIC ACID;2-(4-bromophenyl)-5-methyl-4-oxazoleacetic acid;SCHEMBL4064386;FCVXIPPJDZQRCK-UHFFFAOYSA-N;DTXSID801243445;EN300-18667115;2-(2-(4-BROMOPHENYL)-5-METHYLOXAZOL-4-YL)ACETICACID

Suppliers and Price of 2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:294.98441
Heavy Atom Count:17
Complexity:279

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC=C(C=C2)Br)CC(=O)O

Technology Process of 2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid

There total 7 articles about 2-(4-Bromophenyl)-5-methyl-4-oxazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 328918-83-8
[2-(4-bromophenyl)-5-methyloxazole-4-yl]-acetonitrile

: 328918-82-7
2-(4-bromophenyl)-5-methyl-4-oxazoleacetic acid

Guidance literature:: With potassium hydroxide; In 2-methoxy-ethanol;
DOI:10.1016/j.bmcl.2004.09.031

Reference yield:

: 328918-81-6
2-(4-bromophenyl)-4-(chloromethyl)-5-methyl-1,3-oxazole

: 328918-82-7
2-(4-bromophenyl)-5-methyl-4-oxazoleacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / KI / dimethylformamide

2: 60 percent / KOH / 2-methoxy-ethanol

With potassium hydroxide; potassium iodide; In 2-methoxy-ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.09.031

Reference yield:

: 328918-80-5
4,5-dimethyl-2-(4-bromophenyl)-oxazole oxide

: 328918-82-7
2-(4-bromophenyl)-5-methyl-4-oxazoleacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / POCl₃ / CHCl₃

2: 100 percent / KI / dimethylformamide

3: 60 percent / KOH / 2-methoxy-ethanol

With potassium hydroxide; potassium iodide; trichlorophosphate; In chloroform; 2-methoxy-ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.09.031