trans-3-(3-Pyridyl)acrolein, 98+%

Base Information

• Chemical Name: trans-3-(3-Pyridyl)acrolein, 98+%
• CAS No.: 32986-65-5
• Molecular Formula: C₈H₇NO
• Molecular Weight: 133.15
• Mol file: 32986-65-5.mol

Synonyms:trans-3-(3-Pyridyl)acrolein;3-pyridinepropanoic acid;3-Pyridinepropionic acid;Pyridine-3-propionic acid;

Chemical Property of trans-3-(3-Pyridyl)acrolein, 98+%

Chemical Property:

• Boiling Point: 270℃
• PKA: 3.77±0.11(Predicted)
• Flash Point: 124℃
• PSA: 29.96000
• Density: 1.100
• LogP: 1.29370

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trans-3-(3-Pyridyl)acrolein, 98+%

There total 15 articles about trans-3-(3-Pyridyl)acrolein, 98+% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3-(3-pyridinyl)propionaldehyde (1802-16-0) → trans-3-(3-pyridyl)acrolein (28447-15-6,32986-65-5)

Guidance literature:

With ammonium cerium (IV) nitrate; (2S,5S)-5-benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one; In 1,2-dimethoxyethane; at 25 ℃; for 2h;

DOI:10.1016/j.tetlet.2011.12.131

Reference yield: 70.0%

3-iodopyridine (1120-90-7) + N-allyl-N-methylaniline (6628-07-5) → trans-3-(3-pyridyl)acrolein (28447-15-6,32986-65-5)

Guidance literature:

With tetrabutylammomium bromide; sodium acetate; palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 120 ℃; for 10h; in air;

DOI:10.1039/b917782e

Reference yield: 57.0%

3-iodopyridine (1120-90-7) + allyl alcohol (107-18-6) → trans-3-(3-pyridyl)acrolein (28447-15-6,32986-65-5)

Guidance literature:

With tetrabutyl-ammonium chloride; oxygen; palladium diacetate; sodium hydrogencarbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 60 ℃; for 20h; under 760.051 Torr;

DOI:10.1039/b922351g

upstream raw materials:

3-pyridinecarboxaldehyde

acetaldehyde

(triphenylphosphoranylidene)acetaldehyde

trimethylsilylacetaldehyde tert-butylimine

Downstream raw materials:

3t-[3]pyridyl-acrylaldehyde-(2,4-dinitro-phenylhydrazone)

(E,E)-1-(3-pyridyl)-4-(phenyl)buta-1,3-diene

(1E,3Z)-1-(3-pyridyl)-4-(phenyl)buta-1,3-diene

10-(3-Pyridyl)-deca-3E,5E,7E,9E-tetraen-2-on, Navenon A