3-Chloro-6-fluoropyridazine

Base Information

• Chemical Name: 3-Chloro-6-fluoropyridazine
• CAS No.: 33097-38-0
• Molecular Formula: C4H2ClFN2
• Molecular Weight: 132.52300
• DSSTox Substance ID: DTXSID00465332
• Nikkaji Number: J1.366.880I
• Wikidata: Q82291183
• Mol file: 33097-38-0.mol

Synonyms:3-Chloro-6-fluoropyridazine;33097-38-0;MFCD12547767;Pyridazine, 3-chloro-6-fluoro-;3-chloro-6-fluoro pyridazine;SCHEMBL2562054;DTXSID00465332;AMY24050;AKOS017344365;AS-50123;CS-0137004;FT-0707737;EN300-203476;O10986;Z1618110321

Chemical Property of 3-Chloro-6-fluoropyridazine

Chemical Property:

• Boiling Point: 243.9±20.0 °C(Predicted)
• PKA: -1.04±0.10(Predicted)
• PSA: 25.78000
• Density: 1.439±0.06 g/cm3(Predicted)
• LogP: 1.26910
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 131.9890539
• Heavy Atom Count: 8
• Complexity: 80.4

Purity/Quality:

99%, ^*data from raw suppliers

3-Chloro-6-fluoropyridazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NN=C1F)Cl

Technology Process of 3-Chloro-6-fluoropyridazine

There total 3 articles about 3-Chloro-6-fluoropyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

6-chloro-pyridazin-3-ylamine (5469-69-2) → 6-chloro-3-fluoropyridazine (33097-38-0)

Guidance literature:

With hydrogen fluoride; sodium nitrite; In pyridine; at 0 ℃; for 0.5h;

DOI:10.1021/acs.jmedchem.1c01067

Reference yield: 55.0%

C9H7ClN3(1+)*BF4(1-) → 6-chloro-3-fluoropyridazine (33097-38-0)

Guidance literature:

With potassium fluoride; In acetonitrile; at 80 ℃;

DOI:10.1038/s41557-021-00812-0

Reference yield: 53.0%

3,6-dichlorpyridazine (141-30-0) → 6-chloro-3-fluoropyridazine (33097-38-0) + 3,6-difluoropyridazine (33097-39-1)

Guidance literature:

With triethylamine; 1,8-bis(dimethylamino)naphthalene tris(hydrogen fluoride); at 80 ℃; for 96h;

DOI:10.1016/S0040-4039(00)01054-6

upstream raw materials:

3,6-dichlorpyridazine

6-chloro-pyridazin-3-ylamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 33097-38-0 3-chloro-6-fluoropyridazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send