Benzene, 1-(1,2-dibromoethyl)-4-methyl-

Base Information

• Chemical Name: Benzene, 1-(1,2-dibromoethyl)-4-methyl-
• CAS No.: 33458-08-1
• Molecular Formula: C9H10Br2
• Molecular Weight: 277.986
• DSSTox Substance ID: DTXSID40470066
• Nikkaji Number: J1.553.094D
• Mol file: 33458-08-1.mol

Synonyms:Benzene, 1-(1,2-dibromoethyl)-4-methyl-;33458-08-1;SCHEMBL8972988;DTXSID40470066

Chemical Property of Benzene, 1-(1,2-dibromoethyl)-4-methyl-

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 277.91288
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(CBr)Br

Technology Process of Benzene, 1-(1,2-dibromoethyl)-4-methyl-

There total 15 articles about Benzene, 1-(1,2-dibromoethyl)-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) → 1-(1,2-dibromoethyl)-4-methylbenzene (33458-08-1)

Guidance literature:

With bromine; In chloroform; at 0 ℃; Inert atmosphere;

DOI:10.1055/s-0036-1589143

Reference yield: 87.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) → 1-(1,2-dibromoethyl)-4-methylbenzene (33458-08-1) + 2-bromo-1-(p-tolyl)ethanol (60655-81-4) + 4-(bromoacetyl)toluene (619-41-0)

Guidance literature:

With sodium bromate; sulfuric acid; sodium bromide; In 1,4-dioxane; water; at 20 ℃; for 6h;

DOI:10.1016/j.tetlet.2009.03.047

Reference yield: 79.0%

1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) → 1-(1,2-dibromoethyl)-4-methylbenzene (33458-08-1) + 2-bromo-1-(p-tolyl)ethanol (60655-81-4)

Guidance literature:

With Oxone; ammonium bromide; In water; acetonitrile; at 20 ℃; for 0.0333333h; regioselective reaction;

DOI:10.1016/j.tetlet.2012.01.026

upstream raw materials:

1-ethenyl-4-methylbenzene

trans-p-methylcinnamic acid

methanol

carbon monoxide

Downstream raw materials:

(E)-4-methylstyrenyl bromide

1-ethenyl-4-methylbenzene

1-(1-bromoethenyl)-4-methylbenzene

2-methyl-5-vinyl-aniline