2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide

Base Information

Chemical Name:2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide
CAS No.:33538-09-9
Molecular Formula:C10H12N2
Molecular Weight:160.219
Hs Code.:2933399090
NSC Number:136282
DSSTox Substance ID:DTXSID60300356
Wikidata:Q82043345
Mol file:33538-09-9.mol

Synonyms:2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide;94059-41-3;2,2-Dichloro-N-(2-chloro-5-(trifluoromethyl)phenyl)acetamide;NSC136282;n1-[2-chloro-5-(trifluoromethyl)phenyl]-2,2-dichloroacetamide;2'-chloro-5'-trifluoromethyldichloroacetanilide;SCHEMBL10970540;DTXSID60300356;AKOS003856186;CCG-243370;NSC-136282;CS-0458856;F31105

Suppliers and Price of 2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-tert-Butyl-isonicotinonitrile
40mg
$ 65.00

SynQuest Laboratories
2-tert-Butylisonicotinonitrile 95.0%
500 mg
$ 192.00

SynQuest Laboratories
2-tert-Butylisonicotinonitrile 95.0%
1 g
$ 292.00

SynQuest Laboratories
2-tert-Butylisonicotinonitrile 95.0%
5 g
$ 975.00

Matrix Scientific
2-tert-Butyl-isonicotinonitrile 95%+
5g
$ 1090.00

Matrix Scientific
2-tert-Butyl-isonicotinonitrile 95%+
500mg
$ 288.00

Matrix Scientific
2-tert-Butyl-isonicotinonitrile 95%+
1g
$ 450.00

Frontier Specialty Chemicals
2-tert-Butylpyridine-4-carbonitrile 97%
1g
$ 233.00

Crysdot
2-(tert-Butyl)isonicotinonitrile 95+%
5g
$ 526.00

Chemenu
2-(tert-Butyl)isonicotinonitrile 95%+
1g
$ 298.00

Total 17 raw suppliers

Chemical Property of 2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide

Chemical Property:

Vapor Pressure:0.0498mmHg at 25°C
Boiling Point:235.5oC at 760 mmHg
Flash Point:93.2oC
PSA：36.68000
Density:1g/cm3
LogP:2.25078
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:304.938881
Heavy Atom Count:17
Complexity:285

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-tert-Butyl-isonicotinonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)NC(=O)C(Cl)Cl)Cl

Technology Process of 2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide

There total 18 articles about 2,2-dichloro-N-[2-chloro-5-(trifluoromethyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 100-48-1
pyridine-4-carbonitrile

: 630-19-3
pivalaldehyde

: 33538-09-9
2-(1,1-Dimethylethyl)pyridine-4-carbonitrile

Guidance literature:: With di-tert-butyl peroxide; manganese(II) acetate; In 1,2-dichloro-benzene; at 130 ℃; for 6h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.9b00366

Reference yield: 79.12%

: 100-48-1
pyridine-4-carbonitrile

: 75-98-9
Trimethylacetic acid

: 33538-09-9
2-(1,1-Dimethylethyl)pyridine-4-carbonitrile

: 37581-48-9
2,2-Bis(1,1-dimethylethyl)pyridine-4-carbonitrile

: 74808-75-6
3-(1,1-Dimethylethyl)pyridine-4-carbonitrile

: 74808-76-7
2,5-di-tert-butyl-4-cyanopyridine

: 115-11-7,15220-85-6
isobutene

: 75-65-0
tert-butyl alcohol

Guidance literature:: With dipotassium peroxodisulfate; sulfuric acid; copper diacetate; silver nitrate; In water; at 57 ℃; for 3h; Product distribution; Rate constant; Mechanism; without cupric acetate, various temperatures and acidities, (NH₄)2S₂O₈ for K₂S₂O₈;
DOI:10.1021/jo01311a039

Reference yield: 71.0%

: 100-48-1
pyridine-4-carbonitrile

: 20859-02-3
L-tert-Leucine

: 33538-09-9
2-(1,1-Dimethylethyl)pyridine-4-carbonitrile

Guidance literature:: pyridine-4-carbonitrile; L-tert-Leucine; With ammonium peroxydisulfate; water; trifluoroacetic acid; In 1,2-dichloro-ethane; at 23 ℃; for 0.0166667h;

With silver nitrate; In 1,2-dichloro-ethane; at 80 ℃; for 24h;
DOI:10.1021/acs.orglett.6b01754