(2R)-2-[(1R)-1-Carboxyethoxy]propanoic acid

Base Information

• Chemical Name: (2R)-2-[(1R)-1-Carboxyethoxy]propanoic acid
• CAS No.: 14711-85-4
• Molecular Formula: C₆H₁₀O₅
• Molecular Weight: 162.142
• NSC Number: 18705
• DSSTox Substance ID: DTXSID00417851
• Wikidata: Q82228064
• Mol file: 14711-85-4.mol

Synonyms:14711-85-4;(2R)-2-[(1R)-1-CARBOXYETHOXY]PROPANOIC ACID;NSC18705;DTXSID00417851;NSC-18705;AG-D-91929

Chemical Property of (2R)-2-[(1R)-1-Carboxyethoxy]propanoic acid

Chemical Property:

• Vapor Pressure: 2.87E-07mmHg at 25°C
• Boiling Point: 392.9°Cat760mmHg
• Flash Point: 168.4°C
• PSA: 83.83000
• Density: 1.308g/cm³
• LogP: -0.05080
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 162.05282342
• Heavy Atom Count: 11
• Complexity: 146

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C(=O)O)OC(C)C(=O)O
• Isomeric SMILES: C[C@H](C(=O)O)O[C@H](C)C(=O)O

Technology Process of (2R)-2-[(1R)-1-Carboxyethoxy]propanoic acid

There total 13 articles about (2R)-2-[(1R)-1-Carboxyethoxy]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

S,S-dilactic acid diethyl ester (125948-52-9) → (2S,2'S)-2,2'-oxydipropionic acid (14711-85-4,18609-85-3,19201-34-4)

Guidance literature:

S,S-dilactic acid diethyl ester; With sodium hydroxide; In methanol; at 20 ℃; Inert atmosphere;

With sulfuric acid; In diethyl ether; Inert atmosphere; Cooling with ice;

DOI:10.1002/chem.201806161

Reference yield:

1,1'-bis(1,1'-carboxyethyl) ether (19201-34-4) → DL-dilactylic acid (14711-85-4,18609-85-3,19201-34-4)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated H₂SO₄

2: water; NH₃ / Trennung der Isomeren erfolgt durch fraktionierte Krystallisation aus Aethanol

3: H₂SO₄

With sulfuric acid; ammonia; water;

Reference yield:

L-dilactylic acid diamide (5460-66-2,20753-84-8,20753-85-9,28619-39-8) → (2S,2'S)-2,2'-oxydipropionic acid (14711-85-4,18609-85-3,19201-34-4)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

tetrachloromethane

L-dilactylic acid diamide

S,S-dilactic acid diethyl ester

D-dilactylic acid diamide

Downstream raw materials:

carbon dioxide

water

acetaldehyde