HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE

Base Information

• Chemical Name: HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE
• CAS No.: 778-18-7
• Molecular Formula: C12H18O3
• Molecular Weight: 210.273
• Mol file: 778-18-7.mol

Synonyms:2,2,4,4,6,6-Hexamethyl-cyclohexane-1,3,5-trione;1,3,5-Cyclohexanetrione, 2,2,4,4,6,6-hexamethyl-;2,2,4,4,6,6-Hexamethyl-1,3,5-cyclohexanetrione;2,2,4,4,6,6-hexamethylcyclohexanetrione;hexamethyl-cyclohexane-1,3,5-trione;Hexamethyl-cyclohexan-1,3,5-trion;2,2,4,4,6,6-Hexamethyl-1,3,5-cyclohexantrion;

Chemical Property of HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE

Chemical Property:

• Vapor Pressure: 0.000407mmHg at 25°C
• Melting Point: 78-80oC
• Boiling Point: 316.5°C at 760 mmHg
• Flash Point: 131.6°C
• PSA: 51.21000
• Density: 0.995g/cm³
• LogP: 1.78590

Purity/Quality:

99% ，98% ^*data from raw suppliers

HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE 99.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE

There total 17 articles about HEXAMETHYLCYCLOHEXANE-1,3,5-TRIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,4,4-tetramethyl-1,3-cyclobutanedione (933-52-8) → 4-isopropylidene-3,3-dimethyl-oxetan-2-one (3173-79-3) + 3,3,5,5-tetramethyl-6-(propan-2-ylidene)-dihydro-3H-pyran-2,4-dione (10319-92-3) + hexamethylcyclohexane-1,3,5-trione (778-18-7)

Guidance literature:

With sodium methylate; In N,N-dimethyl-formamide; for 0.0833333h; Heating;

DOI:10.1007/s00706-007-0689-z

Reference yield:

triphenylmethyl sodium (4303-71-3) → hexamethylcyclohexane-1,3,5-trione (778-18-7)

Guidance literature:

With diethyl ether;

DOI:10.1021/ja01267a103

Reference yield:

2,2,4,4-tetramethyl-1,3-cyclobutanedione (933-52-8) → hexamethylcyclohexane-1,3,5-trione (778-18-7)

Guidance literature:

With sodium methylate; In xylene;

DOI:10.1021/jo01056a030

upstream raw materials:

3,5-dihydroxyphenol

methanol

2,4,6-trimethyl-1,3,5-benzenetriol

sodium methylate

Downstream raw materials:

2,2,4,4,6,6-hexamethyl-cyclohexane-1,3,5-triol

2,4-dimethylpentan-3-one

2,2,4,4,6,6-hexamethyl-1,3,5-trimethylidenecyclohexane

carbon dioxide

Refernces

• 1、 Saaidi, Pierre-Loic,Doridot, Gabriel,Jeanneau, Erwann,Hasserodt, Jens. "Insights into the formation of symmetrical trimers of dialkylated ketenes starting from acid chloride precursors". . p. 1011 - 1018. Retrieved 2008/03/17.