4-Piperidinepropanoic acid, 1-(phenylmethyl)-

Base Information

Chemical Name:4-Piperidinepropanoic acid, 1-(phenylmethyl)-
CAS No.:339333-00-5
Molecular Formula:C15H21NO2
Molecular Weight:247.337
Hs Code.:

Synonyms:3-(1-benzyl-4-piperidyl)propanoic acid;3-(1-Benzyl-piperidin-4-yl)-propionic acid;3-(1-benzylpiperidin-4-yl)propionic acid;

Suppliers and Price of 4-Piperidinepropanoic acid, 1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
3-(1-benzylpiperidin-4-yl)propanoicacid 95%
1g
$ 225.00

Total 3 raw suppliers

Chemical Property of 4-Piperidinepropanoic acid, 1-(phenylmethyl)-

Chemical Property:

Melting Point:78 °C (ethanol)
PSA：40.54000
LogP:2.70130

Purity/Quality:

97% ^*data from raw suppliers

3-(1-benzylpiperidin-4-yl)propanoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Piperidinepropanoic acid, 1-(phenylmethyl)-

There total 13 articles about 4-Piperidinepropanoic acid, 1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 124438-69-3
3-(1-Benzyl-piperidin-4-yl)-propionic acid,ethyl ester

: 339333-00-5
ethyl 3-(1-benzylpiperidin-4-yl)propionic acid

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 12h; pH=4 - 5;
DOI:10.3987/com-01-9213

Reference yield:

: 2564-06-9
N-benzyl-2-chloroacetamide

: 339333-00-5
ethyl 3-(1-benzylpiperidin-4-yl)propionic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: 12.88 g / dioxane; H₂O / 10 h / Heating

2.1: NaH / tetrahydrofuran / 0.25 h / 20 °C

2.2: 54 percent / tetrahydrofuran / 0.5 h / Heating

3.1: 94 percent / H₂ / Pd/C / ethyl acetate / 3 h / 20 °C

4.1: Na; liq. NH₃ / 2 h / -78 - -30 °C

5.1: 433 mg / LiAlH₄ / tetrahydrofuran / 2 h / Heating

6.1: Jones reagent / acetone / 0.17 h / cooling

With lithium aluminium tetrahydride; jones reagent; ammonia; hydrogen; sodium; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; water; ethyl acetate; acetone;
DOI:10.1002/jccs.200200156