2'-Hydroxy-4-methoxychalcone

Base Information

• Chemical Name: 2'-Hydroxy-4-methoxychalcone
• CAS No.: 34000-29-8
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• European Community (EC) Number: 808-150-6
• DSSTox Substance ID: DTXSID701345759
• Nikkaji Number: J124.948G,J856.764F
• Wikidata: Q63398187
• Metabolomics Workbench ID: 73733
• ChEMBL ID: CHEMBL241862

Synonyms:2'-hydroxy-4-methoxychalcone;2-hydroxy-4'-methoxychalcone;4-methoxy-2'-hydroxychalcone

Chemical Property of 2'-Hydroxy-4-methoxychalcone

Chemical Property:

• Melting Point: 81-83 °C
• Boiling Point: 444.8±45.0 °C(Predicted)
• PSA: 46.53000
• Density: 1?+-.0.06 g/cm3(Predicted)
• LogP: 3.29690
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.094294304
• Heavy Atom Count: 19
• Complexity: 316

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=CC(=O)C2=CC=CC=C2O
• Isomeric SMILES: COC1=CC=C(C=C1)/C=C/C(=O)C2=CC=CC=C2O

Technology Process of 2'-Hydroxy-4-methoxychalcone

There total 26 articles about 2'-Hydroxy-4-methoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2'-acetoxy-4-methoxy-trans-chalcone (62536-68-9) → [E]-3-(p-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (34000-29-8)

Guidance literature:

With β‐cyclodextrin; In water; at 60 ℃; for 0.133333h; Microwave irradiation;

DOI:10.1039/c5ra15996b

Reference yield: 97.0%

C18H20O4 → [E]-3-(p-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (34000-29-8)

Guidance literature:

With β‐cyclodextrin; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In water; acetone; at 60 ℃; for 6h; Green chemistry;

DOI:10.1039/c5gc01785h

Reference yield: 95.22%

o-hydroxyacetophenone (118-93-4,104809-67-8) + 4-methoxy-benzaldehyde (123-11-5) → [E]-3-(p-methoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (34000-29-8)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.0194444h; Microwave irradiation;

DOI:10.1016/j.molstruc.2020.127678

upstream raw materials:

o-hydroxyacetophenone

4-methoxy-benzaldehyde

2'-hydroxy-4-methoxychalcone dibromide

2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one

Downstream raw materials:

2'-acetoxy-4'-methoxychalcone

2,3-dihydro-3-hydroxy-7-methoxyflavone

6-p-Methoxyphenyl-6H-<1>benzopyrano<4,3-b><1,8>naphthyridine

(2S,3R)-4,4-Dimethoxy-2-(4-methoxy-phenyl)-chroman-3-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 34000-29-8 2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send