Pyridazine, 3,6-bis(4-methylphenyl)-

Base Information

• Chemical Name: Pyridazine, 3,6-bis(4-methylphenyl)-
• CAS No.: 34102-87-9
• Molecular Formula: C18H16N2
• Molecular Weight: 260.33300
• DSSTox Substance ID: DTXSID90481501
• Nikkaji Number: J1.702.288A
• Mol file: 34102-87-9.mol

Synonyms:Pyridazine, 3,6-bis(4-methylphenyl)-;34102-87-9;3,6-Bis(4-methylphenyl)pyridazine;3,6-Di-p-tolyl-pyridazine;3,6-di-p-tolylpyridazine;SCHEMBL10000254;DTXSID90481501;WVNRHKLKGNMYAQ-UHFFFAOYSA-N;Pyridazine, 3,6-di(4-methylphenyl)-

Chemical Property of Pyridazine, 3,6-bis(4-methylphenyl)-

Chemical Property:

• PSA: 25.78000
• LogP: 4.42740
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 260.131348519
• Heavy Atom Count: 20
• Complexity: 258

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C2=NN=C(C=C2)C3=CC=C(C=C3)C

Technology Process of Pyridazine, 3,6-bis(4-methylphenyl)-

There total 19 articles about Pyridazine, 3,6-bis(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,6-bis(4-methylphenyl)-2,7-dihydro-1,4,5-thiadiazepine (65263-09-4) → 3,6-bis(4-methylphenyl)pyridazine (34102-87-9)

Guidance literature:

In diethylene glycol; for 4h; Heating;

DOI:10.1246/bcsj.62.2608

Reference yield: 94.0%

C18H14I2O2 → 3,6-bis(4-methylphenyl)pyridazine (34102-87-9)

Guidance literature:

With hydrazine hydrate; In ethanol;

DOI:10.1039/c3ra44965c

Reference yield: 89.0%

3,6-dichlorpyridazine (141-30-0) + 4-methylphenylboronic acid (5720-05-8) → 3,6-bis(4-methylphenyl)pyridazine (34102-87-9)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 36h; Inert atmosphere;

DOI:10.1039/c5dt03872c

upstream raw materials:

(Z)-1,4-Bis(4-methylphenyl)but-2-ene-1,4-dione

bis-(1-p-tolyl-ethylidene)-hydrazine

3,6-bis(4-methylphenyl)-2,7-dihydro-1,4,5-thiadiazepine

3,6-di(p-tolyl)-1,2-dithiine