tert-butyl Cyclohexene benzene

Base Information

• Chemical Name: tert-butyl Cyclohexene benzene
• CAS No.: 3419-73-6
• Molecular Formula: C16H22
• Molecular Weight: 214.351
• Mol file: 3419-73-6.mol

Synonyms:1-(4-tert-butylcyclohex-1-enyl)benzene;(4-tert-Butyl-cyclohex-1-enyl)-benzene;4-(tert-butyl)-1-phenylcyclohexene;1-phenyl-4-tert-butylcyclohex-1-ene;(4-tert-butylcyclohex-1-en-1-yl)benzene;1-phenyl-4-tert-butyl-1-cyclohexene;(4RS)-1-phenyl-4-tert-butylcyclohexene;

Chemical Property of tert-butyl Cyclohexene benzene

Chemical Property:

• Refractive Index: 1.5437 (589.3 nm 20℃)
• Boiling Point: 106-107℃ (0.4 Torr)
• Flash Point: 130.9±7.6℃
• PSA: 0.00000
• Density: 0.939±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 4.91620

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl Cyclohexene benzene

There total 33 articles about tert-butyl Cyclohexene benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-tert-butyl-1-iodo-1-cyclohexene (96133-27-6) + phenylboronic acid (98-80-6) → 1-phenyl-4-tert-butylcyclohexene (3419-73-6)

Guidance literature:

With potassium fluoride; 18-crown-6 ether; bis-phenanthrylimidazolium chloride; palladium diacetate; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2005.05.071

Reference yield: 96.0%

4-(tert-butyl)-1-phenylcyclohexanol (19437-01-5) → 1-phenyl-4-tert-butylcyclohexene (3419-73-6)

Guidance literature:

iodine; at 25 ℃; for 0.25h; Further Variations:; Solvents; Temperatures; Product distribution;

DOI:10.1016/j.tetlet.2006.09.154

Reference yield: 95.0%

cis-4-tert-butyl-1-phenylcyclohexanol (17807-26-0) → 1-phenyl-4-tert-butylcyclohexene (3419-73-6)

Guidance literature:

silica gel; toluene-4-sulfonic acid; In benzene; for 0.5h; Ambient temperature;

DOI:10.1055/s-1985-31463

upstream raw materials:

cis-4-tert-butyl-1-phenylcyclohexanol

trans-4-tert-butyl-1-phenylcyclohexanol

lithium diphenylcuprate

1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene

Downstream raw materials:

r-1-phenyl-1,t-2-difluoro-1-t-4-tert-butylcyclohexane

r-1-phenyl-1,c-2-difluoro-t-4-tert-butylcyclohexane

r-1-phenyl-1-fluoro-c-2-chloro-t-4-tert-butylcyclohexane

r-1-phenyl-1-fluoro-c-2-chloro-c-4-tert-butylcyclohexane