3-Fluoropyridine-4-carboxylic acid ethyl ester

Base Information

Chemical Name:3-Fluoropyridine-4-carboxylic acid ethyl ester
CAS No.:343-72-6
Molecular Formula:C8H8FNO2
Molecular Weight:161.22400
Hs Code.:2933399090
Mol file:343-72-6.mol

Synonyms:ethyl 3-fluoroisonicotinate;3-Fluoropyridine-4-carboxylic acid ethyl ester;3-fluoro-isonicotinic acid ethyl ester;3-Fluor-isonicotinsaeure-aethylester;

Suppliers and Price of 3-Fluoropyridine-4-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-fluoro-4-Pyridinecarboxylicacidethylester 97.00%
25G
$ 4320.00

AccelPharmtech
3-fluoro-4-Pyridinecarboxylicacidethylester 97.00%
5G
$ 2330.00

AccelPharmtech
3-fluoro-4-Pyridinecarboxylicacidethylester 97.00%
1G
$ 2070.00

Total 14 raw suppliers

Chemical Property of 3-Fluoropyridine-4-carboxylic acid ethyl ester

Chemical Property:

PSA：37.66000
LogP:2.44390

Purity/Quality:

98%min ^*data from raw suppliers

3-fluoro-4-Pyridinecarboxylicacidethylester 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Fluoropyridine-4-carboxylic acid ethyl ester

There total 12 articles about 3-Fluoropyridine-4-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 4-(ethoxycarbonyl)pyridine-3-diazonium tetrafluoroborate

: 343-72-6
ethyl 3-fluoroisonicotinate

Guidance literature:: With 4-(difluoroiodo)toluene; boron trifluoride diethyl etherate; In chlorobenzene; at 45 ℃; for 36h; Temperature; Reagent/catalyst; Catalytic behavior; Glovebox; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.201802466

Reference yield:

: 14208-83-4
ethyl 3-aminopyridine-4-carboxylate

: 343-72-6
ethyl 3-fluoroisonicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 1 h / 0 - 20 °C / Inert atmosphere

2: boron trifluoride diethyl etherate; 4-(difluoroiodo)toluene / chlorobenzene / 36 h / 45 °C / Glovebox; Sealed tube; Inert atmosphere

With 4-(difluoroiodo)toluene; boron trifluoride diethyl etherate; In ethanol; chlorobenzene; 2: |Balz-Schiemann Reaction;
DOI:10.1002/anie.201802466