3-Benzyl-5,5-diphenylimidazolidine-2,4-dione

Base Information

• Chemical Name: 3-Benzyl-5,5-diphenylimidazolidine-2,4-dione
• CAS No.: 34657-67-5
• Molecular Formula: C22H18N2O2
• Molecular Weight: 342.397
• DSSTox Substance ID: DTXSID60368693
• Nikkaji Number: J708.531A
• Wikidata: Q82155432
• ChEMBL ID: CHEMBL49614
• Mol file: 34657-67-5.mol

Synonyms:3-benzyl-5,5-diphenylimidazolidine-2,4-dione;CHEMBL49614;34657-67-5;3-benzyl-5,5-diphenylhydantoin;SCHEMBL15461433;DTXSID60368693;BDBM50422742;AKOS016988544;AB00979531-01;Z14473614

Chemical Property of 3-Benzyl-5,5-diphenylimidazolidine-2,4-dione

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 342.136827821
• Heavy Atom Count: 26
• Complexity: 496

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CN2C(=O)C(NC2=O)(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 3-Benzyl-5,5-diphenylimidazolidine-2,4-dione

There total 17 articles about 3-Benzyl-5,5-diphenylimidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

benzylurea (538-32-9) + benzil (134-81-6) → 3-benzyl-5,5-diphenyl-imidazolidine-2,4-dione (34657-67-5)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; microwave irradiation;

DOI:10.1021/ol035282x

Reference yield: 49.0%

phenythoin (57-41-0) + benzyl chloride (100-44-7) → 3-benzyl-5,5-diphenyl-imidazolidine-2,4-dione (34657-67-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1007/s00706-013-1149-6

Reference yield: 11.0%

carbon monoxide (201230-82-2) + amino-diphenyl-acetic acid benzylamide → 3-benzyl-5,5-diphenyl-imidazolidine-2,4-dione (34657-67-5)

Guidance literature:

With tungsten hexacarbonyl; iodine; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 35 ℃; for 24h; under 60804.1 Torr; Inert atmosphere;

DOI:10.1021/jo9016138

upstream raw materials:

3-benzyl-2-benzylmercapto-5,5-diphenyl-3,5-dihydro-imidazol-4-one

phenythoin

benzyl chloride

benzylamine

Downstream raw materials:

3-benzyl-1-methyl-5,5-diphenyl-imidazolidine-2,4-dione