4-Fluoro-N-(4-methoxybenzyl)benzamide

Base Information

• Chemical Name: 4-Fluoro-N-(4-methoxybenzyl)benzamide
• CAS No.: 346725-04-0
• Molecular Formula: C₁₅H₁₄FNO₂
• Molecular Weight: 259.28
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID30358081
• Nikkaji Number: J2.218.489J
• Wikidata: Q82138369
• Mol file: 346725-04-0.mol

Synonyms:4-Fluoro-N-(4-methoxybenzyl)benzamide;346725-04-0;4-fluoro-N-[(4-methoxyphenyl)methyl]benzamide;CBMicro_037361;Oprea1_525245;DTXSID30358081;MFCD01359589;STL197953;N-(4-Methoxybenzyl)4-fluorobenzamide;AKOS002707191;BS-23248;BIM-0037121.P001;CS-0451428;A874897

Chemical Property of 4-Fluoro-N-(4-methoxybenzyl)benzamide

Chemical Property:

• Melting Point: 114-115 °C
• Boiling Point: 439.8±35.0 °C(Predicted)
• PKA: 14.12±0.46(Predicted)
• PSA: 38.33000
• Density: 1.185±0.06 g/cm3(Predicted)
• LogP: 3.15520
• Storage Temp.: 2-8°C
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 259.10085685
• Heavy Atom Count: 19
• Complexity: 282

Purity/Quality:

99%min ^*data from raw suppliers

4-Fluoro-N-(4-methoxybenzyl)benzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CNC(=O)C2=CC=C(C=C2)F

Technology Process of 4-Fluoro-N-(4-methoxybenzyl)benzamide

There total 1 articles about 4-Fluoro-N-(4-methoxybenzyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → 4-fluoro-N-(4-methoxybenzyl)benzamide (346725-04-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 40 °C / Inert atmosphere

2: sodium hydroxide; tetrakis(acetonitrile)copper(I)tetrafluoroborate; tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 3 h / 80 °C / Sealed tube; Inert atmosphere

With tetrakis(acetonitrile)copper(I)tetrafluoroborate; tetra-(n-butyl)ammonium iodide; sodium hydroxide; In tetrahydrofuran;

DOI:10.1002/adsc.201500331

upstream raw materials:

4-methoxy-benzaldehyde

Refernces