Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

Base Information

Chemical Name:Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate
CAS No.:349620-39-9
Molecular Formula:C14H19NO4S
Molecular Weight:297.375
Hs Code.:
DSSTox Substance ID:DTXSID80387705
ChEMBL ID:CHEMBL1742190
Mol file:349620-39-9.mol

Synonyms:ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate;349620-39-9;MLS000530697;ethyl 1-(phenylsulfonyl)-3-piperidinecarboxylate;SMR000135675;3-Piperidinecarboxylic acid, 1-(phenylsulfonyl)-, ethyl ester;HMS1543E14;ethyl 1-(benzenesulfonyl)piperidine-3-carboxylate;TimTec1_003270;Oprea1_354541;SCHEMBL612760;CHEMBL1742190;BDBM89892;cid_2904534;1-besylnipecotic acid ethyl ester;DTXSID80387705;HJFLMHXJHDEFND-UHFFFAOYSA-N;HMS2416H24;STK417384;AKOS002662848;AKOS016042889;AB00111504-01;1-(benzenesulfonyl)-3-piperidinecarboxylic acid ethyl ester

Suppliers and Price of Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

Chemical Property:

Boiling Point:422.3±55.0 °C(Predicted)
PSA：72.06000
Density:1.244±0.06 g/cm3(Predicted)
LogP:2.66910
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:297.10347926
Heavy Atom Count:20
Complexity:423

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CCCN(C1)S(=O)(=O)C2=CC=CC=C2

Technology Process of Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

There total 1 articles about Ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 98-09-9
benzenesulfonyl chloride

: 71962-74-8
Ethyl nipecotate

: 349620-39-9
ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 349620-39-9
ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

: 100-58-3
phenylmagnesium bromide

: C₂₄H₂₅NO₃S

Guidance literature:: ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate; phenylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 5h; Cooling with ice;

With water; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.tetlet.2011.11.105

Reference yield:

: 349620-39-9
ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate

: 4294-57-9
para-methylphenylmagnesium bromide

: C₂₆H₂₉NO₃S

Guidance literature:: ethyl 1-(phenylsulfonyl)piperidine-3-carboxylate; para-methylphenylmagnesium bromide; In tetrahydrofuran; at 20 ℃; for 5h; Cooling with ice;

With water; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.tetlet.2011.11.105