Boc-L-alanyl-L-proline benzyl ester

Base Information

Chemical Name:Boc-L-alanyl-L-proline benzyl ester
CAS No.:35084-69-6
Molecular Formula:C20H28N2O5
Molecular Weight:376.453
Hs Code.:
DSSTox Substance ID:DTXSID501154334
Mol file:35084-69-6.mol

Synonyms:Boc-L-alanyl-L-proline benzyl ester;Boc-AlaPro-OBzl;BOC-Ala-Pro-OBzl;35084-69-6;N-t-butyloxycarbonyl-L-alanyl-L-proline benzyl ester;SCHEMBL7265704;YRGOZFGRJADWIU-HOCLYGCPSA-N;DTXSID501154334;AKOS016035502;N-tert.-butoxycarbonyl-L-alanyl-L-proline, benzyl ester;t-butoxycarbonyl-L-alanyl-L-proline, phenylmethyl ester;N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-L-proline phenylmethyl ester

Suppliers and Price of Boc-L-alanyl-L-proline benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Boc-L-alanyl-L-proline benzyl ester

Chemical Property:

PSA：84.94000
LogP:2.96280
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:376.19982200
Heavy Atom Count:27
Complexity:537

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)N1CCCC1C(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C
Isomeric SMILES:C[C@@H](C(=O)N1CCC[C@H]1C(=O)OCC2=CC=CC=C2)NC(=O)OC(C)(C)C

Technology Process of Boc-L-alanyl-L-proline benzyl ester

There total 8 articles about Boc-L-alanyl-L-proline benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 15761-38-3
L-N-Boc-Ala

: 16652-71-4
benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride

: 35084-69-6
N-t-butyloxycarbonyl-L-alanyl-L-proline benzyl ester

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 18h; Inert atmosphere;
DOI:10.1021/acs.orglett.5b00781

Reference yield: 87.0%

: 16652-71-4
benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride

: 16357-59-8
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

: 120791-81-3
N-(ethyloxycarbonyl)-(L)-proline benzyl ester

: 35084-69-6
N-t-butyloxycarbonyl-L-alanyl-L-proline benzyl ester

Guidance literature:: With L-N-Boc-Ala; triethylamine; In dichloromethane; for 40h;

Reference yield: 82.0%

: 15761-38-3
L-N-Boc-Ala

: L-proline benzyl ester trifluoroacetate

: 35084-69-6
N-t-butyloxycarbonyl-L-alanyl-L-proline benzyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 25 ℃; for 16h;