1-(4-Methoxyphenyl)-1-methylhydrazine

Base Information

• Chemical Name: 1-(4-Methoxyphenyl)-1-methylhydrazine
• CAS No.: 35292-54-7
• Molecular Formula: C8H12N2O
• Molecular Weight: 152.196
• DSSTox Substance ID: DTXSID40459356
• Nikkaji Number: J59.964F
• Wikidata: Q82283111
• Mol file: 35292-54-7.mol

Synonyms:1-(4-Methoxyphenyl)-1-methylhydrazine;35292-54-7;Hydrazine, 1-(4-methoxyphenyl)-1-methyl-;SCHEMBL3752368;DTXSID40459356;HZEHBAPKYPEFDS-UHFFFAOYSA-N;N-(4-Methoxy-phenyl)-N-methyl-hydrazine

Chemical Property of 1-(4-Methoxyphenyl)-1-methylhydrazine

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 152.094963011
• Heavy Atom Count: 11
• Complexity: 111

Purity/Quality:

99% ,99.9%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C1=CC=C(C=C1)OC)N

Technology Process of 1-(4-Methoxyphenyl)-1-methylhydrazine

There total 5 articles about 1-(4-Methoxyphenyl)-1-methylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-N-nitroso-p-anisidine (940-11-4) → N-methyl-N-(p-methoxyphenyl)hydrazine (35292-54-7)

Guidance literature:

With zinc;

Reference yield:

N-methyl-N-(4-methoxyphenyl)amine (5961-59-1) → N-methyl-N-(p-methoxyphenyl)hydrazine (35292-54-7)

Guidance literature:

With hydrogenchloride; sodium nitrite; Reduzieren der entstandenen Nitrosoverbindung mit Zinkstaub und verd. Essigsaeure;

DOI:10.1039/jr9330000270

Reference yield:

butane-2,3-dione-mono-(4-methoxy-phenylhydrazone) (136953-50-9) + methyl iodide (74-88-4) → N-methyl-N-(p-methoxyphenyl)hydrazine (35292-54-7)

Guidance literature:

With hydrogenchloride; sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; hydrazine hydrate; Yield given. Multistep reaction; 1.) CH₂Cl₂, 2.) EtOH, 100 deg C;

upstream raw materials:

N-methyl-N-nitroso-p-anisidine

methyl bromide

4-Methoxyphenylhydrazine

N-methyl-N-(4-methoxyphenyl)amine

Downstream raw materials:

3-ethyl-1,2-dimethyl-5-methoxyindole

<(5-methoxy-1-methyl)indol-2-yl>carboxylic acid

5-methoxy-1,2-dimethyl-1H-indole

(Z)-2-[N'-(4-Methoxy-phenyl)-N'-methyl-hydrazino]-4-oxo-4-phenyl-but-2-enoic acid methyl ester