Carbamic acid, [2,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2-[[2-(trimethylsilyl)ethoxy]meth yl]indeno[1,2-c]pyrazol-5-yl]-, phenyl ester

Base Information

• Chemical Name: Carbamic acid, [2,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2-[[2-(trimethylsilyl)ethoxy]meth yl]indeno[1,2-c]pyrazol-5-yl]-, phenyl ester
• CAS No.: 360792-99-0
• Molecular Formula: C30H31N3O5Si
• Molecular Weight: 541.679
• Mol file: 360792-99-0.mol

Synonyms:

Chemical Property of Carbamic acid, [2,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2-[[2-(trimethylsilyl)ethoxy]meth yl]indeno[1,2-c]pyrazol-5-yl]-, phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, [2,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2-[[2-(trimethylsilyl)ethoxy]meth yl]indeno[1,2-c]pyrazol-5-yl]-, phenyl ester

There total 3 articles about Carbamic acid, [2,4-dihydro-3-(4-methoxyphenyl)-4-oxo-2-[[2-(trimethylsilyl)ethoxy]meth yl]indeno[1,2-c]pyrazol-5-yl]-, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

phenyl chloroformate (1885-14-9) + 5-amino-3-(4-methoxy-phenyl)-2-(2-trimethylsilanyl-ethoxymethyl)-2H-indeno[1,2-c]pyrazol-4-one (807628-23-5) → [3-(4-methoxy-phenyl)-4-oxo-2-(2-trimethylsilanyl-ethoxymethyl)-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-carbamic acid phenyl ester (360792-99-0)

Guidance literature:

With potassium carbonate; In acetone; at 50 ℃;

DOI:10.1016/j.bmcl.2004.09.023

Reference yield:

(2-trimethylethylsilylethoxy)methyl chloride (76513-69-4) → [3-(4-methoxy-phenyl)-4-oxo-2-(2-trimethylsilanyl-ethoxymethyl)-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-carbamic acid phenyl ester (360792-99-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / Et₃N / CHCl₃ / Heating

2: 75 percent / K₂CO₃ / acetone / 50 °C

With potassium carbonate; triethylamine; In chloroform; acetone;

DOI:10.1016/j.bmcl.2004.09.023

Reference yield:

5-amino-3-(4-methoxy-phenyl)-2H-indeno[1,2-c]pyrazol-4-one (247149-96-8) → [3-(4-methoxy-phenyl)-4-oxo-2-(2-trimethylsilanyl-ethoxymethyl)-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-carbamic acid phenyl ester (360792-99-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / Et₃N / CHCl₃ / Heating

2: 75 percent / K₂CO₃ / acetone / 50 °C

With potassium carbonate; triethylamine; In chloroform; acetone;

DOI:10.1016/j.bmcl.2004.09.023

upstream raw materials:

phenyl chloroformate

5-amino-3-(4-methoxy-phenyl)-2-(2-trimethylsilanyl-ethoxymethyl)-2H-indeno[1,2-c]pyrazol-4-one

(2-trimethylethylsilylethoxy)methyl chloride

5-amino-3-(4-methoxy-phenyl)-2H-indeno[1,2-c]pyrazol-4-one

Downstream raw materials:

C₃₀H₃₂N₆O₅Si

C₃₀H₃₂N₆O₅Si

C₂₆H₃₁N₅O₆Si

C₂₆H₃₀N₆O₆Si