1-Piperidinecarboxylic acid, 4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo yl]amino]methyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1-Piperidinecarboxylic acid, 4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo yl]amino]methyl]-, 1,1-dimethylethyl ester
CAS No.:362697-41-4
Molecular Formula:C30H36N4O6
Molecular Weight:548.639
Hs Code.:
Mol file:362697-41-4.mol

1-Piperidinecarboxylic acid,
4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo
yl]amino]methyl]-, 1,1-dimethylethyl ester

Synonyms:

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Chemical Property of 1-Piperidinecarboxylic acid, 4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo yl]amino]methyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 1-Piperidinecarboxylic acid, 4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo yl]amino]methyl]-, 1,1-dimethylethyl ester

There total 6 articles about 1-Piperidinecarboxylic acid, 4-[(hydroxyamino)carbonyl]-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzo yl]amino]methyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 362697-41-4
1-[(1,1-dimethylethoxy)carbonyl]-N-hydroxy-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzoyl]amino]methyl]-4-piperidinecarboxamide

Guidance literature:

Reference yield:

: 362703-34-2
1-tert-butyl 4-methyl 4-cyanopiperidine-1,4-dicarboxylate

: 362697-41-4
1-[(1,1-dimethylethoxy)carbonyl]-N-hydroxy-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzoyl]amino]methyl]-4-piperidinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: H₂; aq. HCl / PtO₂ / methanol

2: BOP; N-methylmorpholine / dimethylformamide

3: NH₂OH; KOH / methanol

With 4-methyl-morpholine; hydrogenchloride; potassium hydroxide; hydrogen; hydroxylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; platinum(IV) oxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.02.015

Reference yield:

: 159635-50-4
Bis-(2-bromo-ethyl)-carbamic acid tert-butyl ester

: 362697-41-4
1-[(1,1-dimethylethoxy)carbonyl]-N-hydroxy-4-[[[4-[(2-methyl-4-quinolinyl)methoxy]benzoyl]amino]methyl]-4-piperidinecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: NaH / tetrahydrofuran

2: H₂; aq. HCl / PtO₂ / methanol

3: BOP; N-methylmorpholine / dimethylformamide

4: NH₂OH; KOH / methanol

With 4-methyl-morpholine; hydrogenchloride; potassium hydroxide; hydrogen; hydroxylamine; sodium hydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; platinum(IV) oxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.02.015