(2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine

Base Information

Chemical Name:(2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine
CAS No.:364066-92-2
Molecular Formula:C13H19FN2
Molecular Weight:222.306
Hs Code.:
DSSTox Substance ID:DTXSID40477777
Wikidata:Q82310687
Mol file:364066-92-2.mol

Synonyms:364066-92-2;(2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine;(2S,5R)-1-[(4-FLUOROPHENYL)METHYL]-2,5-DIMETHYLPIPERAZINE;(2S,5R)-1-(4-FLUOROBENZYL)-2,5-DIMETHYLHEXAHYDROPYRAZINE;SCHEMBL3176427;DTXSID40477777;VWFLVEICKAOIRL-MNOVXSKESA-N;MFCD18904340;AKOS015994505;SS-3083;(trans)-1-(4-fluorobenzyl)-2,5-dimethylpiperazine;(trans)-1-(4-fluoro-benzyl)-2,5-dimethyl-piperazine;(trans)-1-(4-fluorobenzyl)-2,5-dimethyl-piperazine

Suppliers and Price of (2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:222.15322678
Heavy Atom Count:16
Complexity:214

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CNC(CN1CC2=CC=C(C=C2)F)C
Isomeric SMILES:C[C@H]1CN[C@@H](CN1CC2=CC=C(C=C2)F)C

Technology Process of (2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine

There total 8 articles about (2S,5R)-1-(4-Fluorobenzyl)-2,5-dimethylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2C₄H₆O₆*C₁₃H₁₉FN₂

: 364066-92-2
(2S,5R)-1-(4-fluorobenzyl)-2,5-dimethylpiperazine

Guidance literature:: With sodium hydroxide; In dichloromethane; water; at 20 ℃; for 1.16667h;

Reference yield:

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 2815-34-1,1119702-25-8
2,5-dimethyl-piperazine

: 364066-92-2
(2S,5R)-1-(4-fluorobenzyl)-2,5-dimethylpiperazine

Guidance literature:: With tetrabutylammomium bromide; sodium hydroxide; In cyclohexane; water; at 35 - 45 ℃; for 6h; Inert atmosphere;
DOI:10.1021/op7000386