2,4-Diphenylbenzo[h]quinazoline

Base Information

• Chemical Name: 2,4-Diphenylbenzo[h]quinazoline
• CAS No.: 36547-38-3
• Molecular Formula: C24H16N2
• Molecular Weight: 332.39700
• European Community (EC) Number: 668-065-3
• DSSTox Substance ID: DTXSID10392746
• Nikkaji Number: J2.287.003C
• Wikidata: Q82191134
• Mol file: 36547-38-3.mol

Synonyms:2,4-diphenylbenzo[h]quinazoline;2,4-diphenylbenzo(H)quinazoline;36547-38-3;BIDD:GT0520;SCHEMBL10942572;DTXSID10392746;AKOS024337534

Chemical Property of 2,4-Diphenylbenzo[h]quinazoline

Chemical Property:

• PSA: 25.78000
• LogP: 6.11700
• XLogP3: 6.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 332.131348519
• Heavy Atom Count: 26
• Complexity: 451

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-DIPHENYLBENZO(H)QUINAZOLINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC(=NC3=C2C=CC4=CC=CC=C43)C5=CC=CC=C5

Technology Process of 2,4-Diphenylbenzo[h]quinazoline

There total 13 articles about 2,4-Diphenylbenzo[h]quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-benzyl-N′-(naphthalen-1-yl)benzimidamide → 1,3-diphenylbenzo[h]quinazoline (36547-38-3)

Guidance literature:

With carbon tetrabromide; rose bengal; potassium carbonate; In dimethyl sulfoxide; at 100 ℃; for 4h; Irradiation;

DOI:10.1021/acs.joc.5b02366

Reference yield: 80.0%

2,4-diphenyl-5,6-dihydrobenzoquinazoline (148256-51-3) → 1,3-diphenylbenzo[h]quinazoline (36547-38-3)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-benzene; at 120 ℃; for 3h;

DOI:10.1016/j.tet.2006.01.010

Reference yield: 70.0%

1-amino-naphthalene (134-32-7) + benzaldehyde (100-52-7) → 1,3-diphenylbenzo[h]quinazoline (36547-38-3)

Guidance literature:

With ammonium iodide; oxygen; dimethyl sulfoxide; In chlorobenzene; at 150 ℃; for 12h;

DOI:10.1039/c8gc02654h

upstream raw materials:

N-(1-naphthyl)benzimidoyl chloride

benzonitrile

2,4-diphenyl-5,6-dihydrobenzoquinazoline

3,4-dihydronaphthalene-1(2H)-one