3-Chloro-4-Methoxybenzoyl Chloride

Base Information

Chemical Name:3-Chloro-4-Methoxybenzoyl Chloride
CAS No.:36590-49-5
Molecular Formula:C8H6Cl2O2
Molecular Weight:205.04
Hs Code.:
Mol file:36590-49-5.mol

Synonyms:3-chloro-4-methoxy-benzoyl chloride;3-Chloro-4-methoxybenzoyl Chloride;3-Chlor-4-methoxy-benzoylchlorid;3-chloro-4-methoxybenzoic acid chloride;

Suppliers and Price of 3-Chloro-4-Methoxybenzoyl Chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-4-methoxybenzoylChloride
1g
$ 165.00

Atlantic Research Chemicals
3-Chloro-4-methoxybenzoylchloride 95%
1gm:
$ 279.23

Alichem
3-Chloro-4-methoxybenzoylchloride
1g
$ 1564.50

Alichem
3-Chloro-4-methoxybenzoylchloride
500mg
$ 782.40

Total 4 raw suppliers

Chemical Property of 3-Chloro-4-Methoxybenzoyl Chloride

Chemical Property:

Boiling Point:120 - 125 °C (1 mmHg)
PSA：26.30000
LogP:2.72760

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-4-methoxybenzoylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-Chloro-4-methoxybenzoyl Chloride is used in the synthesis of diphenolic azoles as potent estrogen β-receptor ligands, useful in the treatment of certain inflammatory conditions or illnesses. Also is used in the synthesis of N-acetyltransferase inhibitors that act as anti-tubercular agents.

Technology Process of 3-Chloro-4-Methoxybenzoyl Chloride

There total 5 articles about 3-Chloro-4-Methoxybenzoyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 37908-96-6
3-chloro-4-methoxy benzoic acid

: 36590-49-5
3-chloro-4-methoxybenzoyl chloride

Guidance literature:: With thionyl chloride;
DOI:10.1021/ac60099a016

Reference yield:

: 79-37-8
oxalyl dichloride

: 37908-96-6
3-chloro-4-methoxy benzoic acid

: 36590-49-5
3-chloro-4-methoxybenzoyl chloride

Guidance literature:: In chloroform; N,N-dimethyl-formamide;

Reference yield:

: 100-09-4
4-methoxybenzoic acid

: 36590-49-5
3-chloro-4-methoxybenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / glacial CH₃COOH, Cl₂ / Ambient temperature

2: SOCl₂, DMF / ethyl acetate / 10 h / Heating

With thionyl chloride; chlorine; acetic acid; N,N-dimethyl-formamide; In ethyl acetate;
DOI:10.1021/jm00393a020