2,3,5-triMethoxybenzoic acid

Base Information

• Chemical Name: 2,3,5-triMethoxybenzoic acid
• CAS No.: 36873-96-8
• Molecular Formula: C10H12O5
• Molecular Weight: 212.202
• Mol file: 36873-96-8.mol

Synonyms:2,3,5-trimethoxy-benzoic acid;2,3,5-Trimethoxy-benzoesaeure;

Chemical Property of 2,3,5-triMethoxybenzoic acid

Chemical Property:

• PSA: 64.99000
• LogP: 1.41060
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2,3,5-Trimethoxybenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5-triMethoxybenzoic acid

There total 16 articles about 2,3,5-triMethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

carbon dioxide (124-38-9,18923-20-1) + 1-bromo-2,3,5-trimethoxybenzene (23030-39-9) → 2,3,5-trimethoxybenzoic acid (36873-96-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran;

DOI:10.1016/S0040-4039(00)60137-5

Reference yield: 84.0%

2,3,5-trimethoxy-benzonitrile (75510-58-6) → 2,3,5-trimethoxybenzoic acid (36873-96-8)

Guidance literature:

With sodium hydroxide; In methanol; water; for 72h; Heating;

Reference yield:

2,3,5-trimethoxy-benzaldehyde (5556-84-3) → 2,3,5-trimethoxybenzoic acid (36873-96-8)

Guidance literature:

With potassium hydroxide; potassium permanganate;

DOI:10.1039/jr9390001922 DOI:10.1021/ja01359a033

upstream raw materials:

diazomethane

5-hydroxy-2,3-dimethoxy-benzoic acid

2,3,5-trimethoxy-benzaldehyde

1-bromo-2,3,5-trimethoxybenzene

Downstream raw materials:

N-(2-Hydroxy-1,1-dimethyl-ethyl)-2,3,5-trimethoxy-benzamide

4-(1-methylethyl)-2,3,5-trimethoxybenzoic acid

4'-decyl-2-methoxy-2'-(2'',3'',5''-trimethoxybenzoyloxy)acetophenone

methyl 4-(1-methylethyl)-2,3,5-trimethoxybenzoate

Refernces

• 1、 Majetich, George,Zhang, Yong,Tian, Xinrong,Britton, Jonathan E.,Li, Yang,Phillips, Ryan. "Synthesis of (±)- and (+)-perovskone". experimental part. p. 10129 - 10146. Retrieved 2012/02/03.
• 2、 Majetich, George,Zhang, Yong. "Concise synthesis of (±)-perovskone". . p. 4979 - 4980. Retrieved 2007/10/02.