5556-84-3

Basic information

• Product Name: 2,3,5-TRIMETHOXYBENZALDEHYDE
• Synonyms: 2,3,5-TRIMETHOXYBENZALDEHYDE
• CAS NO: 5556-84-3
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Mol File: 5556-84-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63 °C
• Boiling Point: 326.796°C at 760 mmHg
• Flash Point: 144.913°C
• Appearance: /
• Density: 1.133g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• CAS DataBase Reference: 2,3,5-TRIMETHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5-TRIMETHOXYBENZALDEHYDE(5556-84-3)
• EPA Substance Registry System: 2,3,5-TRIMETHOXYBENZALDEHYDE(5556-84-3)

Safety Data

• Hazardous Substances Data: 5556-84-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 5556-84-3 differently. You can refer to the following data:
1. 2,3,5-Trimethoxybenzaldehyde is used in the preparation of imine derivatives which might exhibit glycosidase inhibitors. It is also used in the preparation of phenylalkylamine analogs with psychoactiv e properties. Starting reagent for the preparation of flavonoids.
2. 2,3,5-Trimethoxybenzaldehyde is used in the preparation of imine derivatives which might exhibit glycosidase inhibitors. It is also used in the preparation of phenylalkylamine analogs with psychoactive properties. Starting reagent for the preparation of flavonoids.

InChI:InChI=1/C10H12O4/c1-12-8-4-7(6-11)10(14-3)9(5-8)13-2/h4-6H,1-3H3

Upstream product

• 65162-29-0 3,5-Dimethoxy-2-hydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 13330-65-9 2,4-dimethoxyphenol 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 75510-58-6 2,3,5-trimethoxy-benzonitrile 
• 93092-15-0 1-cyano-5-hydroxy-2,3-dimethoxybenzene 
• 93092-14-9 1-bromo-5-hydroxy-2,3-dimethoxybenzene 
• 6948-30-7 5-bromoveratralaldehyde 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 6324-49-8 2,3-dimethoxy-5-nitrobenzaldehyde 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 

Downstream Products

• 36873-96-8 2,3,5-trimethoxybenzoic acid 
• 107301-77-9 2,3,5-trimethoxy-benzyl alcohol 
• 94272-89-6 2,3,5-trimethoxybenzylaminoacetaldehyde diethyl acetal 
• 85122-21-0 2-Methoxystypandrone 
• 122849-61-0 (E)-3-methoxycarbonyl-4-(2,3,5-trimethoxyphenyl)but-3-enoic acid 
• 122849-62-1 methyl 4-acetoxy-5,7,8-trimethoxynaphthalene-2-carboxylate 
• 40243-89-8 1,2,5-trimethoxy-3-vinylbenzene 
• 1222844-25-8 trans-2,3,5,4'-tetramethoxystilbene 
• 5273-82-5 (E)-1,2,5-trimethoxy-3-(prop-1-en-1-yl)benzene 
• 5273-81-4 cis-2,3,5-Trimethoxy-1-propenyl-benzol 
• 146202-78-0 2,3,5-trimethoxyphenylacetonitrile 
• 110361-77-8 methyl 2,3,5-trimethoxybenzoate 
• 93092-18-3 5,6,7-Trimethoxy-2-(2,3,5-trimethoxy-phenyl)-chromen-4-one 
• 93746-14-6 5,6,7-Trimethoxy-2-(2,3,5-trimethoxy-phenyl)-chroman-4-one 

Relevant articles and documents

An Improved Preparation of the p-Tropoquinone Mono- and Diacetals by Thallium(III) Nitrate Oxidation of 2-Alkoxy-5-hydroxytropones

The thallium(III) nitrate-oxidation of 2-alkoxy-5-hydroxytropones gave, in good yields, the mono- and diacetals of tropoquinones, which can be used for the introduction of oxygen functions to the seven-membered nucleus and preparation of the substituted t

Attempt to synthesize 2,3,5,4′-tetrahydroxystilbene derived from 2,3,5,4′-tetrahydroxystilbene-2-O-β-glucoside (THSG)

An attempt to synthesize aglycone 1 derived from 2,3,5,4′-tetrahydroxystilbene-2-O-β-glucoside (THSG) via the Wittig reaction and Mizoroki-Heck reaction is described. In the Wittig protocol, 2,3,5,4′-tetramethoxystilbene 2 was obtained. Additionally, a palladium-catalyzed Mizoroki-Heck reaction strategy yielded 2-aryl-2,3-dihydrobenzofuran 13 instead of derivative 12 in good yield.

Synthesis of 2-Methoxystypandrone: Comments on the Structure of Ventilaginone

The structure of 2-methoxystypandrone a naphthoquinone isolated from Polygonum cuspidatum, Rhamnus fallax, and Ventilago calyculata is confirmed by synthesis as 6-acetyl-5-hydroxy-2-methoxy-7-methylnaphthalene-1,4-dione (1).The structure proposed for ventilaginone, an unusual naphthalene isolated from Ventilago maderaspatana, 8,9-dimethoxy-5-methylnaphtho-1,3-dioxin-4-yl methyl ketone (17), is shown by synthesis to be erroneous.Alternative structures are considered.