1-Methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene

Base Information

• Chemical Name: 1-Methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene
• CAS No.: 3722-61-0
• Molecular Formula: C17H20O4
• Molecular Weight: 288.343
• DSSTox Substance ID: DTXSID40367124
• Nikkaji Number: J680.719D
• Wikidata: Q82152758
• Mol file: 3722-61-0.mol

Synonyms:1-methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene;Benzene, 1,1'-[1,3-propanediylbis(oxy)]bis[2-methoxy-;3722-61-0;CBMicro_004906;Cambridge id 5362780;DTXSID40367124;1,3-Bis(2-methoxyphenoxy)propane;SMSF0005723;CB07244;BIM-0005066.P001;SR-01000207100;SR-01000207100-1

Chemical Property of 1-Methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 288.13615911
• Heavy Atom Count: 21
• Complexity: 246

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1OCCCOC2=CC=CC=C2OC

Technology Process of 1-Methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene

There total 6 articles about 1-Methoxy-2-[3-(2-methoxyphenoxy)propoxy]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,3-dimesyloxypropane (15886-84-7) + 2-methoxy-phenol (90-05-1) → 1,3-bis(2’-methoxyphenoxy)propane (3722-61-0)

Guidance literature:

2-methoxy-phenol; With caesium carbonate; In acetonitrile; at 20 ℃; for 3h; Inert atmosphere; Reflux;

1,3-dimesyloxypropane; In acetonitrile; for 24h; Inert atmosphere; Reflux;

DOI:10.3998/ark.5550190.0011.717

Reference yield:

2-methoxy-phenol (90-05-1) + 1,3-dibromo-propane (109-64-8) → 1,3-bis(2’-methoxyphenoxy)propane (3722-61-0)

Guidance literature:

With sodium ethanolate;

Reference yield:

2-methoxy-phenol (90-05-1) + 1.3-chlorobromopropane (109-70-6) → 1,3-bis(2’-methoxyphenoxy)propane (3722-61-0)

Guidance literature:

With sodium ethanolate;

DOI:10.1016/S0040-4020(01)98986-0

upstream raw materials:

2-methoxy-phenol

1,3-dibromo-propane

1,3-bis(2-hydroxyphenoxy)propane

dimethyl sulfate

Downstream raw materials:

2-(3-chloro-propoxy)-phenol

1-(o-Hydroxyphenoxy)-3-(o-methoxyphenoxy)-propan

1,3-bis(2-hydroxyphenoxy)propane