O-tert-Butyl-carbonyl-4-hydroxy Myrtenol

Base Information

Chemical Name:O-tert-Butyl-carbonyl-4-hydroxy Myrtenol
CAS No.:374559-42-9
Molecular Formula:C15H24O3
Molecular Weight:252.354
Hs Code.:
DSSTox Substance ID:DTXSID70461321
Nikkaji Number:J1.567.070C
Mol file:374559-42-9.mol

Synonyms:O-tert-Butyl-carbonyl-4-hydroxy Myrtenol;374559-42-9;[(1R,5S)-4-hydroxy-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl 2,2-dimethylpropanoate;SCHEMBL17414527;DTXSID70461321;2,2-DIMETHYL-PROPIONIC ACID (1R,5S);-4-hydroxy-6,6-dimethyl-bicyclo[3.1.1]hept-2-en-2-ylmethyl ester

Suppliers and Price of O-tert-Butyl-carbonyl-4-hydroxy Myrtenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
O-tert-Butyl-carbonyl-4-hydroxyMyrtenol
25mg
$ 165.00

Medical Isotopes, Inc.
O-tert-Butyl-carbonyl-4-hydroxyMyrtenol
250 mg
$ 2200.00

Medical Isotopes, Inc.
O-tert-Butyl-carbonyl-4-hydroxyMyrtenol
25 mg
$ 650.00

Total 1 raw suppliers

Chemical Property of O-tert-Butyl-carbonyl-4-hydroxy Myrtenol

Chemical Property:

PSA：46.53000
LogP:2.53890
Storage Temp.:Refrigerator
Solubility.:Dichloromethane, Ethyl Acetate, MEthanol
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:252.17254462
Heavy Atom Count:18
Complexity:387

Purity/Quality:: O-tert-Butyl-carbonyl-4-hydroxyMyrtenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2CC1C(=CC2O)COC(=O)C(C)(C)C)C
Isomeric SMILES:CC1([C@@H]2C[C@H]1C(=CC2O)COC(=O)C(C)(C)C)C
Uses Intermediate in the preparation of HU 210 (H673500).

Technology Process of O-tert-Butyl-carbonyl-4-hydroxy Myrtenol

There total 4 articles about O-tert-Butyl-carbonyl-4-hydroxy Myrtenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 76163-96-7
(1S,5R)-4-[(2,2-dimethylpropoyloxy)methyl]-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-one

: 374559-42-9
(1S,5R)-4-[(2,2-dimethylpropoyloxy)methyl]-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-ol

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃;

Reference yield:

: 19894-97-4
(1R)-Myrtenol

: 374559-42-9
(1S,5R)-4-[(2,2-dimethylpropoyloxy)methyl]-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / CH₂Cl₂; pyridine / 4 h / 0 °C

2: 53 percent / CrO₃; 3,5-dimethylpyrazole / CH₂Cl₂ / 4 h / -20 °C

3: 89 percent / LiAlH(O-Bu)3 / tetrahydrofuran; diethyl ether / 4 h / 0 - 20 °C

With 3,5-dimethyl-1H-pyrazole; chromium(VI) oxide; lithium tri(tert-butoxy)aluminum hydride; In tetrahydrofuran; pyridine; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4020(01)00729-3

Reference yield:

: 3282-30-2
pivaloyl chloride

: 374559-42-9
(1S,5R)-4-[(2,2-dimethylpropoyloxy)methyl]-6,6-dimethylbicyclo[3.1.1]hept-3-en-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / CH₂Cl₂; pyridine / 4 h / 0 °C

2: 53 percent / CrO₃; 3,5-dimethylpyrazole / CH₂Cl₂ / 4 h / -20 °C

3: 89 percent / LiAlH(O-Bu)3 / tetrahydrofuran; diethyl ether / 4 h / 0 - 20 °C

With 3,5-dimethyl-1H-pyrazole; chromium(VI) oxide; lithium tri(tert-butoxy)aluminum hydride; In tetrahydrofuran; pyridine; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4020(01)00729-3