2,4-Cyclohexadien-1-one, 4-bromo-6,6-dimethoxy-

Base Information

• Chemical Name: 2,4-Cyclohexadien-1-one, 4-bromo-6,6-dimethoxy-
• CAS No.: 376396-10-0
• Molecular Formula: C8H9BrO3
• Molecular Weight: 233.062
• Mol file: 376396-10-0.mol

Synonyms:2,4-Cyclohexadien-1-one,4-bromo-6,6-dimethoxy;4-bromo-6,6-dimethoxy-2,4-cyclohexadien-1-one;4-bromo-6,6-dimethoxycyclohexa-2,4-dienone;

Chemical Property of 2,4-Cyclohexadien-1-one, 4-bromo-6,6-dimethoxy-

Chemical Property:

• Boiling Point: 284.6±40.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.52±0.1 g/cm3(Predicted)
• LogP: 1.39320

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Cyclohexadien-1-one, 4-bromo-6,6-dimethoxy-

There total 2 articles about 2,4-Cyclohexadien-1-one, 4-bromo-6,6-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + 4-bromoguaiacol (7368-78-7) → 4-bromo-6,6-dimethoxy-2,4-cyclohexadien-1-one (376396-10-0)

Guidance literature:

With [bis(acetoxy)iodo]benzene; at 0 ℃;

DOI:10.1021/ol0164132

Reference yield:

methanol (67-56-1) + 4-bromo-phenol (106-41-2) → 4,4-dimethoxycyclohexa-2,5-dienone (935-50-2) + 4-Bromo-4-methoxy-cyclohexa-2,5-dienone + 4-bromo-6,6-dimethoxy-2,4-cyclohexadien-1-one (376396-10-0)

Guidance literature:

With [bis(acetoxy)iodo]benzene; for 0.0833333h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0040-4020(97)00110-5

Reference yield: 82.0%

benzenesufonyl hydrazide (80-17-1) + 4-bromo-6,6-dimethoxy-2,4-cyclohexadien-1-one (376396-10-0) → 4-bromo-5-(phenylsulfonyl)benzene-1,2-diol

Guidance literature:

With water; In acetonitrile; at 70 ℃; for 2h; Reagent/catalyst; Solvent; Temperature; Green chemistry;

DOI:10.1002/ejoc.201701038

upstream raw materials:

methanol

4-bromo-phenol

4-bromoguaiacol

Downstream raw materials:

4-bromo-6-(2,4-dimethoxyphenyl)-2-methoxyphenol

4-bromo-1-(2,4-dimethoxyphenoxy)-2-methoxybenzene

1-(5-bromo-2-hydroxy-3-methoxyphenyl)naphthalen-2-ol

1-(5-bromo-2-hydroxy-3-methoxyphenyl)-3-methoxynaphthalen-2-ol