4,4'-Diphenoxybenzophenone

Base Information

• Chemical Name: 4,4'-Diphenoxybenzophenone
• CAS No.: 14984-21-5
• Deprecated CAS: 1817604-21-9
• Molecular Formula: C25H18O3
• Molecular Weight: 366.416
• Hs Code.: 2914509090
• European Community (EC) Number: 403-390-4
• UNII: 2L24EX5O0X
• DSSTox Substance ID: DTXSID7065835
• Nikkaji Number: J129.650G
• Wikidata: Q27254879
• Mol file: 14984-21-5.mol

Synonyms:4,4'-Diphenoxybenzophenone;14984-21-5;Bis(4-phenoxyphenyl)methanone;Methanone, bis(4-phenoxyphenyl)-;Benzophenone, 4,4'-diphenoxy-;UNII-2L24EX5O0X;4,4/'-Diphenoxybenzophenone;2L24EX5O0X;C25H18O3;Oprea1_141132;Oprea1_465437;SCHEMBL235530;4,4'-bis(phenoxy)benzophenone;DTXSID7065835;Bis(4-phenoxyphenyl)methanone #;4,4'-DIPHENOXY BENZOPHENONE;MFCD00077969;AKOS015855135;C25-H18-O3;PS-10979;CS-0206993;FT-0617099;A808966;Q27254879

Chemical Property of 4,4'-Diphenoxybenzophenone

Chemical Property:

• Vapor Pressure: 1.08E-10mmHg at 25°C
• Melting Point: 148-150°C
• Refractive Index: 1.623
• Boiling Point: 514.4 °C at 760 mmHg
• Flash Point: 257.3 °C
• PSA: 35.53000
• Density: 1.186 g/cm³
• LogP: 6.50220
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 6.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 366.125594432
• Heavy Atom Count: 28
• Complexity: 420

Purity/Quality:

98%min ^*data from raw suppliers

Bis(4-phenoxyphenyl)methanone 99% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)C3=CC=C(C=C3)OC4=CC=CC=C4

Technology Process of 4,4'-Diphenoxybenzophenone

There total 13 articles about 4,4'-Diphenoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1,1-bis(4-phenoxyphenyl)ethylene (129965-23-7) → 4,4'-bis(phenoxy)benzophenone (14984-21-5) + 3,3,6,6-Tetrakis(4-phenoxyphenyl)-1,2-dioxane

Guidance literature:

With dichloro-acetic acid; oxygen; In acetonitrile; at 13 ℃; Product distribution; Rate constant; Mechanism; Irradiation; also in the presence of LiClO₄;

DOI:10.1021/jo00074a035

Reference yield: 85.0%

4,4'-Difluorobenzophenone (345-92-6) + phenol (108-95-2,27073-41-2) → 4,4'-bis(phenoxy)benzophenone (14984-21-5)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; toluene; at 150 - 165 ℃; for 2h;

DOI:10.1016/j.polymer.2021.123639

Reference yield: 67.0%

4-Bromodiphenyl ether (101-55-3) + chloroformic acid ethyl ester (541-41-3) → 4,4'-bis(phenoxy)benzophenone (14984-21-5)

Guidance literature:

chloroformic acid ethyl ester; With cobalt 2,2'-bipyridine dibromide; 3-chloroprop-1-ene; trifluoroacetic acid; zinc; In acetonitrile; at 20 ℃; for 0.333333h;

4-Bromodiphenyl ether; In acetonitrile; at 20 ℃; for 8h;

DOI:10.1002/ejoc.201600738

upstream raw materials:

diphenylether

2,3,5,6-tetramethylbenzoic acid

bis(4-bromophenyl)methanone

potassium phenolate

Downstream raw materials:

bis(4-phenoxyphenyl)methanol

4,4'-diphenoxy-benzhydrylamine

Refernces

• 1、 Rérat, Alice,Michon, Christophe,Agbossou-Niedercorn, Francine,Gosmini, Corinne. "Synthesis of Symmetrical Diaryl Ketones by Cobalt-Catalyzed Reaction of Arylzinc Reagents with Ethyl Chloroformate". . p. 4554 - 4560. Retrieved 2016/09/23.
• 2、 Schreivogel, Alina,Maurer, Joerg,Winter, Rainer,Baro, Angelika,Laschat, Sabine. "Synthesis and electrochemical properties of tetrasubstituted tetraphenylethenes". . p. 3395 - 3404. Retrieved 2007/10/03.