diethyl N,N-dimethylcarbamoylmethylphosphonate

Base Information

Chemical Name:diethyl N,N-dimethylcarbamoylmethylphosphonate
CAS No.:3842-86-2
Molecular Formula:C8H18NO4P
Molecular Weight:223.209
Hs Code.:
DSSTox Substance ID:DTXSID00456225
Wikidata:Q82278507
Mol file:3842-86-2.mol

Synonyms:3842-86-2;diethyl (2-(dimethylamino)-2-oxoethyl)phosphonate;diethyl N,N-dimethylcarbamoylmethylphosphonate;Phosphonic acid, [2-(dimethylamino)-2-oxoethyl]-, diethyl ester;2-diethoxyphosphoryl-N,N-dimethylacetamide;starbld0000683;SCHEMBL578486;DTXSID00456225;SPNSSEKVTXYNNH-UHFFFAOYSA-N;2-(diethylphosphono)-N,N-dimethylacetamide;CS-0096159;D75727;Diethyl[2-(dimethylamino)-2-oxoethyl]phosphonate;N,N-Di-methylcarbamoylmethyl phosphonic acid diethyl ester

Suppliers and Price of diethyl N,N-dimethylcarbamoylmethylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of diethyl N,N-dimethylcarbamoylmethylphosphonate

Chemical Property:

XLogP3:-0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:223.09734505
Heavy Atom Count:14
Complexity:219

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(CC(=O)N(C)C)OCC

Technology Process of diethyl N,N-dimethylcarbamoylmethylphosphonate

There total 3 articles about diethyl N,N-dimethylcarbamoylmethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 122-52-1
triethyl phosphite

: 2675-89-0
2-chloro-N,N-dimethylacetamide

: 3842-86-2
diethyl N,N-dimethylcarbamoylmethylphosphonate

Guidance literature:: at 165 ℃; for 5.5h;
DOI:10.1139/V06-112

Reference yield: 68.0%

: 683-08-9
Diethyl methylphosphonate

: 3842-86-2
diethyl N,N-dimethylcarbamoylmethylphosphonate

Guidance literature:: With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -60 ℃;

Reference yield:

: 127-19-5,116057-81-9
N,N-dimethyl acetamide

: 814-49-3
diethyl chlorophosphate

: 3842-86-2
diethyl N,N-dimethylcarbamoylmethylphosphonate

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, hexane, 12-15 deg C, 2.) THF, hexane, RT,;
DOI:10.1016/S0040-4020(01)89078-5