(1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol

Base Information

Chemical Name:(1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol
CAS No.:52253-64-2
Molecular Formula:C₁₇H₂₁NO
Molecular Weight:255.36
Hs Code.:
NSC Number:24534
DSSTox Substance ID:DTXSID20417893
Nikkaji Number:J305.014I
Wikidata:Q82228121
Mol file:52253-64-2.mol

Synonyms:52253-64-2;(1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol;NSC24534;(1R,2S)-N-Benzylephedrine;DTXSID20417893;NSC-24534

Suppliers and Price of (1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol

Chemical Property:

Vapor Pressure:1.17E-06mmHg at 25°C
Boiling Point:386.3°C at 760 mmHg
Flash Point:145.6°C
Density:1.071g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:255.162314293
Heavy Atom Count:19
Complexity:244

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C1=CC=CC=C1)O)N(C)CC2=CC=CC=C2
Isomeric SMILES:C[C@@H]([C@@H](C1=CC=CC=C1)O)N(C)CC2=CC=CC=C2

Technology Process of (1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol

There total 14 articles about (1R,2S)-2-[benzyl(methyl)amino]-1-phenylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 299-42-3,7009-81-6,90-83-5,6912-63-6
ephedrine

: 100-39-0
benzyl bromide

: 90-85-7,52253-64-2,52305-21-2,75097-44-8,75110-91-7,88762-93-0
(1R,2S)-1-phenyl-2-(N-methyl-N-benzylamino)propan-1-ol

Guidance literature:: In N,N-dimethyl-formamide; at 85 ℃; for 96h;
DOI:10.1039/b408836k

Reference yield: 96.0%

: 258827-43-9
(2rac,4S,5R)-3,4-dimethyl-2,5-diphenyl-1,3-oxazolidine

: 90-85-7,52253-64-2,52305-21-2,75097-44-8,75110-91-7,88762-93-0
(1R,2S)-1-phenyl-2-(N-methyl-N-benzylamino)propan-1-ol

Guidance literature:: With chloro-trimethyl-silane; sodium cyanoborohydride; In acetonitrile;

Reference yield: 87.0%

: 16735-30-1
2-(N-benzyl-N-methylamino)-1-phenylpropan-1-one

: 90-85-7,52253-64-2,52305-21-2,75097-44-8,75110-91-7,88762-93-0
(1RS,2RS)-2-(benzyl-methyl-amino)-1-phenyl-propan-1-ol

Guidance literature:: With polymethylhydrosiloxane; tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 3h;
DOI:10.1021/jo0260544