{[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile

Base Information

Chemical Name:{[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile
CAS No.:85106-72-5
Molecular Formula:C12H11 N3 O S
Molecular Weight:245.305
Hs Code.:

Synonyms:Malononitrile,[p-anisidino(methylthio)methylene]- (7CI); Propanedinitrile, [[(4-methoxyphenyl)amino](methylthio)methylene]-(9CI); 2-[[(4-Methoxyphenyl)amino](methylsulfanyl)methylene]malononitrile; NSC327943

Suppliers and Price of {[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of {[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile

Chemical Property:

Vapor Pressure:9.84E-06mmHg at 25°C
Boiling Point:372.1°Cat760mmHg
Flash Point:178.8°C
Density:1.271g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of {[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile

There total 4 articles about {[(4-methoxyphenyl)amino](methylsulfanyl)methylidene}propanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 5147-80-8
[Bis(methylthio)methylene]malononitrile

: 104-94-9
4-methoxy-aniline

: 85106-72-5
2-cyano-3-(4-methoxyphenylamino)-3-methylsulfanylacrylonitrile

Guidance literature:: In methanol; for 15h; Heating;
DOI:10.1248/cpb.55.881

Reference yield: 90.0%

: 2284-20-0
4-Methoxyphenyl isothiocyanate

: 109-77-3
malononitrile

: 74-88-4
methyl iodide

: 85106-72-5
2-cyano-3-(4-methoxyphenylamino)-3-methylsulfanylacrylonitrile

Guidance literature:: malononitrile; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 1h; Sealed tube;

4-Methoxyphenyl isothiocyanate; In N,N-dimethyl-formamide; at 0 - 20 ℃; Sealed tube;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Sealed tube;
DOI:10.1039/d1ob01151k

Reference yield:

: 104-94-9
4-methoxy-aniline

: 85106-72-5
2-cyano-3-(4-methoxyphenylamino)-3-methylsulfanylacrylonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene / 3 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h

2.2: 1 h / 20 °C

2.3: 4 h / 20 °C

With sodium hydride; In N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1002/cmdc.201500304