3-(Dimethylamino)-1,1-diphenylpropan-1-ol

Base Information

• Chemical Name: 3-(Dimethylamino)-1,1-diphenylpropan-1-ol
• CAS No.: 4320-42-7
• Molecular Formula: C17H21NO
• Molecular Weight: 255.36
• Hs Code.: 2922199090
• DSSTox Substance ID: DTXSID00195783
• Wikidata: Q83068843
• ChEMBL ID: CHEMBL1617431
• Mol file: 4320-42-7.mol

Synonyms:3-(dimethylamino)-1,1-diphenylpropan-1-ol;4320-42-7;Benzhydrol, alpha-(2-(dimethylamino)ethyl)-;BRN 2124654;alpha-(2-(Dimethylamino)ethyl)benzhydrol;1,1-Diphenyl-3-(dimethylamino)-1-propanol;3-(dimethylamino)-1,1-diphenyl-1-propanol;Oprea1_679724;Oprea1_800156;CBDivE_014992;CHEMBL1617431;SCHEMBL11638488;DTXSID00195783;STK103300;AKOS003658515;NCGC00245715-01;LS-32359;AG-690/11629181

Chemical Property of 3-(Dimethylamino)-1,1-diphenylpropan-1-ol

Chemical Property:

• Vapor Pressure: 3.44E-07mmHg at 25°C
• Boiling Point: 402.2°C at 760 mmHg
• Flash Point: 152.7°C
• PSA: 23.47000
• Density: 1.061g/cm³
• LogP: 2.87420
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 255.162314293
• Heavy Atom Count: 19
• Complexity: 234

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC(C1=CC=CC=C1)(C2=CC=CC=C2)O

Technology Process of 3-(Dimethylamino)-1,1-diphenylpropan-1-ol

There total 16 articles about 3-(Dimethylamino)-1,1-diphenylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl ether (60-29-7,927820-24-4) + trimethyl-(2-oxo-2-phenylethyl)-ammonium bromide (24472-77-3) + phenyllithium (591-51-5) → 3-dimethylamino-1,1-diphenyl-propan-1-ol (4320-42-7) + Phenyl vinyl ketone (768-03-6,26742-84-7)

Guidance literature:

Behandeln des Reaktionsgemisches mit Wasser;

Reference yield:

C23H32BNO2 → 3-dimethylamino-1,1-diphenyl-propan-1-ol (4320-42-7)

Guidance literature:

With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; hexane; water; at 0 - 20 ℃;

DOI:10.1055/s-0035-1562447

Reference yield:

methyl 3-(dimethylamino)propionate (3853-06-3) + phenylmagnesium bromide → 3-dimethylamino-1,1-diphenyl-propan-1-ol (4320-42-7)

Guidance literature:

In diethyl ether;

DOI:10.1021/ja01076a031

upstream raw materials:

ethyl 3-(N,N-dimethylamino)propionate

2-diphenylmethoxy-N,N-dimethylethanamine

1-[(2-dimethylamino-ethoxy)-diphenyl-acetyl]-piperidine

diethyl ether

Downstream raw materials:

(3,3-diphenyl-allyl)-dimethyl-amine

1-cyclohexyl-3-dimethylamino-1-phenyl-propan-1-ol

(3-chloro-3,3-diphenyl-propyl)-dimethyl-amine

normethadone